Evidence map›Paper›PMID 36146181›Full record

ArticleSensors (Basel, Switzerland)2022

Deep Learning for Daily Monitoring of Parkinson's Disease Outside the Clinic Using Wearable Sensors.

Roozbeh Atri, Kevin Urban, Barbara Marebwa, Tanya Simuni, Caroline Tanner, Andrew Siderowf, Mark Frasier, Magali Haas, Lee Lancashire

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Roozbeh AtriCohen Veterans Bioscience, New York, NY 10018, USA.ORCID 0000-0003-4915-656X
Kevin UrbanCohen Veterans Bioscience, New York, NY 10018, USA.ORCID 0000-0003-0478-7528
Barbara MarebwaThe Michael J Fox Foundation for Parkinson's Research, New York, NY 10163, USA.ORCID 0000-0002-5664-0408
Tanya SimuniFeinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Caroline TannerDepartment of Neurology, Weill Institute for Neurosciences University of California, San Francisco, CA 94143, USA.
Andrew SiderowfDepartment of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.
Mark FrasierThe Michael J Fox Foundation for Parkinson's Research, New York, NY 10163, USA.ORCID 0000-0002-1730-0603
Magali HaasCohen Veterans Bioscience, New York, NY 10018, USA.
Lee LancashireCohen Veterans Bioscience, New York, NY 10018, USA.ORCID 0000-0003-4835-4847

Funding

Cohen Veterans Bioscience COH-0003Michael J. Fox Foundation MJFF-020749
6 · The paper itself

Abstract

Now that wearable sensors have become more commonplace, it is possible to monitor individual healthcare-related activity outside the clinic, unleashing potential for early detection of events in diseases such as Parkinson's disease (PD). However, the unsupervised and "open world" nature of this type of data collection make such applications difficult to develop. In this proof-of-concept study, we used inertial sensor data from Verily Study Watches worn by individuals for up to 23 h per day over several months to distinguish between seven subjects with PD and four without. Since motor-related PD symptoms such as bradykinesia and gait abnormalities typically present when a PD subject is walking, we initially used human activity recognition (HAR) techniques to identify walk-like activity in the unconstrained, unlabeled data. We then used these "walk-like" events to train one-dimensional convolutional neural networks (1D-CNNs) to determine the presence of PD. We report classification accuracies near 90% on single 5-s walk-like events and 100% accuracy when taking the majority vote over single-event classifications that span a duration of one day. Though based on a small cohort, this study shows the feasibility of leveraging unconstrained wearable sensor data to accurately detect the presence or absence of PD.

Indexed as

Deep LearningParkinson DiseaseWearable Electronic DevicesGaitHumansHypokinesiadeep learninghuman activity recognitionParkinson’s diseasewearable sensors

Identifiers

PMID36146181
PMCPMC9502239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.