Evidence map›Paper›PMID 36145936›Full record

ReviewPolymers2022

Application of Nano-Inspired Scaffolds-Based Biopolymer Hydrogel for Bone and Periodontal Tissue Regeneration.

Sheikha A Alkhursani, Mohamed Mohamady Ghobashy, Samera Ali Al-Gahtany, Abeer S Meganid, Shady M Abd El-Halim, Zubair Ahmad, Farhat S Khan, Gamal Abdel Nasser Atia, Simona Cavalu

Abstract readReview
In one paragraph

Review in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
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  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Hydrogel Microparticles for Bone Regeneration.Gels (Basel, Switzerland) · 2023
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sheikha A AlkhursaniFaculty of Science and Humanities-Jubail, Imam Abdulrahman Bin Faisal University, Jubail 31441, Saudi Arabia.
Mohamed Mohamady GhobashyRadiation Research of Polymer Chemistry Department, National Center for Radiation Research and Technology (NCRRT), Atomic Energy Authority, Cairo 11787, Egypt.ORCID 0000-0003-0968-1423
Samera Ali Al-GahtanyFaculty of Science, University of Jeddah, Jeddah 21959, Saudi Arabia.
Abeer S MeganidFaculty of Science and Humanities-Jubail, Imam Abdulrahman Bin Faisal University, Jubail 31441, Saudi Arabia.
Shady M Abd El-HalimDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, October 6 University, 6th of October City, Giza 12585, Egypt.ORCID 0000-0002-2716-4676
Zubair AhmadUnit of Bee Research and Honey Production, Faculty of Science, King Khalid University, Abha 61413, Saudi Arabia.
Farhat S KhanBiology Department, College of Arts and Sciences, Dehran Al-Junub, King Khalid University, Abha 61413, Saudi Arabia.
Gamal Abdel Nasser AtiaDepartment of Oral Medicine, Periodontology and Diagnosis, Faculty of Dentistry, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0002-7040-8496
Simona CavaluFaculty of Medicine and Pharmacy, University of Oradea, P-ta 1 Decembrie 10, 410087 Oradea, Romania.ORCID 0000-0001-7810-8925

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review's objectives are to provide an overview of the various kinds of biopolymer hydrogels that are currently used for bone tissue and periodontal tissue regeneration, to list the advantages and disadvantages of using them, to assess how well they might be used for nanoscale fabrication and biofunctionalization, and to describe their production processes and processes for functionalization with active biomolecules. They are applied in conjunction with other materials (such as microparticles (MPs) and nanoparticles (NPs)) and other novel techniques to replicate physiological bone generation more faithfully. Enhancing the biocompatibility of hydrogels created from blends of natural and synthetic biopolymers can result in the creation of the best scaffold match to the extracellular matrix (ECM) for bone and periodontal tissue regeneration. Additionally, adding various nanoparticles can increase the scaffold hydrogel stability and provide a number of biological effects. In this review, the research study of polysaccharide hydrogel as a scaffold will be critical in creating valuable materials for effective bone tissue regeneration, with a future impact predicted in repairing bone defects.

Indexed as

bone generationcollagennanoscaleperiodontalpolysaccharideprotein

Identifiers

PMID36145936
PMCPMC9504130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.