Evidence map›Paper›PMID 36145871›Full record

ReviewPolymers2022

Electrospun Nanofiber Composites for Drug Delivery: A Review on Current Progresses.

Renatha Jiffrin, Saiful Izwan Abd Razak, Mohamad Ikhwan Jamaludin, Amir Syahir Amir Hamzah, Muadz Ahmad Mazian, Muhammad Azan Tamar Jaya, Mohammed Z Nasrullah, Mohammed Majrashi, Abdulrahman Theyab, Ahmed A Aldarmahi and 3 more

Abstract readReview
In one paragraph

Review in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Renatha JiffrinBioinspired Device and Tissue Engineering Research Group, School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, Skudai 81300, Johor, Malaysia.
Saiful Izwan Abd RazakBioinspired Device and Tissue Engineering Research Group, School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, Skudai 81300, Johor, Malaysia.ORCID 0000-0001-7477-0284
Mohamad Ikhwan JamaludinBioinspired Device and Tissue Engineering Research Group, School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, Skudai 81300, Johor, Malaysia.ORCID 0000-0003-3756-1357
Amir Syahir Amir HamzahNanobiotechnology Research Group, Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.ORCID 0000-0002-3305-7957
Muadz Ahmad MazianFaculty of Applied Science, Universiti Teknologi MARA, Cawangan Negeri Sembilan, Kampus Kuala Pilah, Kuala Pilah 72000, Negeri Sembilan, Malaysia.
Muhammad Azan Tamar JayaKolej GENIUS Insan, Universiti Sains Islam Malaysia, Nilai 71800, Negeri Sembilan, Malaysia.
Mohammed Z NasrullahDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-4755-0742
Mohammed MajrashiDepartment of Pharmacology, Faculty of Medicine, University of Jeddah, Jeddah 23881, Saudi Arabia.ORCID 0000-0001-5752-7389
Abdulrahman TheyabDepartment of Laboratory & Blood Bank, Security Forces Hospital, P.O. Box 14799, Mecca 21955, Saudi Arabia.ORCID 0000-0002-6152-7709
Ahmed A AldarmahiBasic Science Department, College of Science and Health Professions, King Saud bin Abdulaziz University for Health Sciences, National Guard-Health Affairs, P.O. Box 9515, Jeddah 21423, Saudi Arabia.ORCID 0000-0001-7137-5238
Zuhier AwanDepartment of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-4176-335X
Mohamed M Abdel-DaimDepartment of Pharmaceutical Sciences, Pharmacy Program, Batterjee Medical College, P.O. Box 6231, Jeddah 21442, Saudi Arabia.ORCID 0000-0002-4341-2713
Abul Kalam AzadFaculty of Pharmacy, MAHSA University, Bandar Saujana Putra, Jenjarom 42610, Selangor, Malaysia.

Funding

Ministry of Higher Education Malaysia for the Fundamental Research Grant Scheme and Geran Penyelidikan MyRA Lepasan PhD FRGS/1/2020/STG02/UPM/02/13 (01-01-20-2223FR/5540355) and (GM LPHD 5/3 (128/2021))
6 · The paper itself

Abstract

A medication's approximate release profile should be sustained in order to generate the desired therapeutic effect. The drug's release site, duration, and rate must all be adjusted to the drug's therapeutic aim. However, when designing drug delivery systems, this may be a considerable hurdle. Electrospinning is a promising method of creating a nanofibrous membrane since it enables drugs to be placed in the nanofiber composite and released over time. Nanofiber composites designed through electrospinning for drug release purposes are commonly constructed of simple structures. This nanofiber composite produces matrices with nanoscale fiber structure, large surface area to volume ratio, and a high porosity with small pore size. The nanofiber composite's large surface area to volume ratio can aid with cell binding and multiplication, drug loading, and mass transfer processes. The nanofiber composite acts as a container for drugs that can be customized to a wide range of drug release kinetics. Drugs may be electrospun after being dissolved or dispersed in the polymer solution, or they can be physically or chemically bound to the nanofiber surface. The composition and internal structure of the nanofibers are crucial for medicine release patterns.

Indexed as

drug deliverydrug releaseelectrospinningnanofibernanofiber composite

Identifiers

PMID36145871
PMCPMC9506405

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.