Evidence map›Paper›PMID 36145610›Full record

ReviewPharmaceutics2022

Lactoferrin-Conjugated Nanoparticles as New Antivirals.

Malgorzata Krzyzowska, Martyna Janicka, Emilia Tomaszewska, Katarzyna Ranoszek-Soliwoda, Grzegorz Celichowski, Jarosław Grobelny, Pawel Szymanski

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Malgorzata KrzyzowskaMilitary Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland.ORCID 0000-0002-8409-3974
Martyna JanickaMilitary Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland.
Emilia TomaszewskaDepartment of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 163 St., 90-236 Lodz, Poland.
Katarzyna Ranoszek-SoliwodaDepartment of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 163 St., 90-236 Lodz, Poland.ORCID 0000-0001-8522-3593
Grzegorz CelichowskiDepartment of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 163 St., 90-236 Lodz, Poland.
Jarosław GrobelnyDepartment of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 163 St., 90-236 Lodz, Poland.
Pawel SzymanskiMilitary Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland.ORCID 0000-0003-3438-7509
University of Łódź · PLMedical University of Lodz · PLWarsaw University of Life Sciences · PLWojskowy Instytut Higieny i Epidemiologii · PL

Funding

Polish National Science Centre grant no. 2018/31/B/NZ6/02606
6 · The paper itself

Abstract

Lactoferrin is an iron-binding glycoprotein with multiple functions in the body. Its activity against a broad spectrum of both DNA and RNA viruses as well as the ability to modulate immune responses have made it of interest in the pharmaceutical and food industries. The mechanisms of its antiviral activity include direct binding to the viruses or its receptors or the upregulation of antiviral responses by the immune system. Recently, much effort has been devoted to the use of nanotechnology in the development of new antivirals. In this review, we focus on describing the antiviral mechanisms of lactoferrin and the possible use of nanotechnology to construct safe and effective new antiviral drugs.

Indexed as

lactoferrinnanoparticlesviruses

Identifiers

PMID36145610
PMCPMC9504495
OpenAlexW4295973400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.