Evidence map›Paper›PMID 36145605›Full record

ArticlePharmaceutics2022

Gut Microbiota and Bile Acids Mediate the Clinical Benefits of YH1 in Male Patients with Type 2 Diabetes Mellitus: A Pilot Observational Study.

Yueh-Hsiang Huang, Yi-Hong Wu, Hsiang-Yu Tang, Szu-Tah Chen, Chih-Ching Wang, Wan-Jing Ho, Yi-Hsuan Lin, Geng-Hao Liu, Pei-Yeh Lin, Chi-Jen Lo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yueh-Hsiang HuangDepartment of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taipei 105, Taiwan.
Yi-Hong WuDepartment of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taipei 105, Taiwan.
Hsiang-Yu TangMetabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan.
Szu-Tah ChenDivision of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan 333, Taiwan.
Chih-Ching WangDivision of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan 333, Taiwan.
Wan-Jing HoDivision of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan 333, Taiwan.
Yi-Hsuan LinDivision of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan 333, Taiwan.
Geng-Hao LiuGraduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan 333, Taiwan.
Pei-Yeh LinDepartment of Medical Nutrition Therapy, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Chi-Jen LoMetabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0003-4439-8033
Yuan-Ming YehGenomic Medicine Core Laboratory, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan 333, Taiwan.ORCID 0000-0001-8720-947X
Mei-Ling ChengMetabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0003-2006-133X
Chang Gung University · TWChang Gung Memorial Hospital · TWChang Gung University of Science and Technology · TW

Funding

Chang Gung Memorial Hospital Research Program CMRPG1K0011Ministry of Science and Technology (Taiwan) MOST 110-2320-B-182A-004
6 · The paper itself

Abstract

Our previous clinical trial showed that a novel concentrated herbal extract formula, YH1 (

Indexed as

bile acidsChinese herbal medicinegut microbiotatype 2 diabetesYH1

Identifiers

PMID36145605
PMCPMC9505101
OpenAlexW4296425609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.