Evidence map›Paper›PMID 36145494›Full record

ArticlePathogens (Basel, Switzerland)2022

Exposure to Veterinary Antibiotics via Food Chain Disrupts Gut Microbiota and Drives Increased

Yehao Liu, Yifan Wu, Jie Wu, Xin Li, Lingling Yu, Ke Xie, Mingyi Zhang, Lingling Ren, Yanli Ji, Yuhui Li

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  5. Review
  6. Veterinary sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yehao LiuDepartmen of Hygiene Inspection and Quarantine, School of Public Health, Anhui Medical University, Hefei 230032, China.ORCID 0000-0002-6381-6440
Yifan WuDepartmen of Hygiene Inspection and Quarantine, School of Public Health, Anhui Medical University, Hefei 230032, China.
Jie WuDepartmen of Hygiene Inspection and Quarantine, School of Public Health, Anhui Medical University, Hefei 230032, China.
Xin LiDepartmen of Hygiene Inspection and Quarantine, School of Public Health, Anhui Medical University, Hefei 230032, China.
Lingling YuDepartmen of Hygiene Inspection and Quarantine, School of Public Health, Anhui Medical University, Hefei 230032, China.
Ke XieDepartmen of Hygiene Inspection and Quarantine, School of Public Health, Anhui Medical University, Hefei 230032, China.
Mingyi ZhangDepartmen of Hygiene Inspection and Quarantine, School of Public Health, Anhui Medical University, Hefei 230032, China.
Lingling RenDepartmen of Hygiene Inspection and Quarantine, School of Public Health, Anhui Medical University, Hefei 230032, China.
Yanli JiDepartmen of Hygiene Inspection and Quarantine, School of Public Health, Anhui Medical University, Hefei 230032, China.
Yuhui LiSchool of Biological Food and Environment, Hefei University, Hefei 230000, China.
Anhui Medical University · CNHefei University · CN

Funding

Department of Science and Technology of Anhui Province 1908085MH287Peak subject of Anhui Medical University 0301001844
6 · The paper itself

Abstract

Exposure to veterinary antibiotics (VAs) and preferred as veterinary antibiotics (PVAs) via the food chain is unavoidable for their extensive use not only for treating bacterial infections, but also for use as growth promoters in livestock and aquaculture. One of the consequences is the disturbance of gut microbiota. However, its impact on the virulence and drug resistance of opportunistic pathogens is still unclear. In this study, a total of 26 antibiotics were detected in the urine of 300 young undergraduates in Anhui Province. We found that excessive intake of milk was positively correlated to high levels of VAs and PVAs. It led to the dysbiosis of gut microbiota characterized by high abundance of Bacteroidetes and Proteobacteria. The increase in Proteobacteria was mainly due to a single operational taxonomic unit (OTU) of

Indexed as

Escherichia coligut microbiotapreferred as veterinary antibioticstranscriptome analysisveterinary antibioticsvirulence

Identifiers

PMID36145494
PMCPMC9500718
OpenAlexW4296350441

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.