Evidence map›Paper›PMID 36145471›Full record

ReviewPathogens (Basel, Switzerland)2022

Determinants of Virus Variation, Evolution, and Host Adaptation.

Katherine LaTourrette, Hernan Garcia-Ruiz

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
14.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 72 citations in OpenAlex.

  1. Blue Light Receptor PHR2-Mediated Spectrum Antiviral Immunity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  13. Review
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  15. Patterns of Recombination in Coronaviruses.International journal of molecular sciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Katherine LaTourretteNebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.ORCID 0000-0001-8248-5707
Hernan Garcia-RuizNebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.ORCID 0000-0002-4681-470X
University of Nebraska–Lincoln · US

Funding

Recognition and recruitment of RNA viruses into RNA silencing pathwaysR01GM120108 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI GARCIA-RUIZ, HERNAN · 2016 to 2020
$1.3M
NIGMS NIH HHS R01 GM120108NIH HHS R01GM120108
6 · The paper itself

Abstract

Virus evolution is the change in the genetic structure of a viral population over time and results in the emergence of new viral variants, strains, and species with novel biological properties, including adaptation to new hosts. There are host, vector, environmental, and viral factors that contribute to virus evolution. To achieve or fine tune compatibility and successfully establish infection, viruses adapt to a particular host species or to a group of species. However, some viruses are better able to adapt to diverse hosts, vectors, and environments. Viruses generate genetic diversity through mutation, reassortment, and recombination. Plant viruses are exposed to genetic drift and selection pressures by host and vector factors, and random variants or those with a competitive advantage are fixed in the population and mediate the emergence of new viral strains or species with novel biological properties. This process creates a footprint in the virus genome evident as the preferential accumulation of substitutions, insertions, or deletions in areas of the genome that function as determinants of host adaptation. Here, with respect to plant viruses, we review the current understanding of the sources of variation, the effect of selection, and its role in virus evolution and host adaptation.

Indexed as

co-evolutionhost adaptationmutationquasispeciesreassortmentrecombinationselection pressurevirus evolution

Identifiers

PMID36145471
PMCPMC9501407
OpenAlexW4296761299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.