Evidence map›Paper›PMID 36145411›Full record

ArticlePathogens (Basel, Switzerland)2022

Emergent and Neglected Equine Filariosis in Egypt: Species Diversity and Host Immune Response.

Faten A M Abo-Aziza, Seham H M Hendawy, Hend H A M Abdullah, Amira El Namaky, Younes Laidoudi, Oleg Mediannikov

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. A meta-analysis onParasitology · 2025
    Review
  2. An investigation of the prevalence of equine filariosis in North and Northeast of Iran.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Faten A M Abo-AzizaDepartment of Parasitology and Animal Diseases, Veterinary Research Institute, National Research Centre, Dokki, Giza 12622, Egypt.
Seham H M HendawyDepartment of Parasitology and Animal Diseases, Veterinary Research Institute, National Research Centre, Dokki, Giza 12622, Egypt.
Hend H A M AbdullahDepartment of Parasitology and Animal Diseases, Veterinary Research Institute, National Research Centre, Dokki, Giza 12622, Egypt.ORCID 0000-0002-8821-6361
Amira El NamakyDepartment of Parasitology and Animal Diseases, Veterinary Research Institute, National Research Centre, Dokki, Giza 12622, Egypt.
Younes LaidoudiAix Marseille Université, IRD, AP-HM, MEPHI, IHU-Méditerranée Infection, 13005 Marseille, France.ORCID 0000-0001-8819-3019
Oleg MediannikovAix Marseille Université, IRD, AP-HM, MEPHI, IHU-Méditerranée Infection, 13005 Marseille, France.ORCID 0000-0001-6039-2008
National Research Centre · EGAix-Marseille Université · FRUniversity Frères Mentouri Constantine 1 · DZ

Funding

Institut Francais d'Egypte 30652Institut Hospitalo-Universitaire (IHU) Méditerranée Infection, the National Research Agency under the program "Investissements d'avenir", reference ANR-10-IAHU-03, the Région Provence-Alpes-Côte d'Azur and European funding FEDER PRIMI. FEDER PRIMIScience and Technology Development Fund 30652
6 · The paper itself

Abstract

Equine filariosis (EF) is a neglected vector-borne disease caused by nematode species belonging to the Onchocercidae and Setariidae families. Aside from their zoonotic potential, some species are responsible for serious health problems in equids worldwide, leading to significant economic difficulties. Here, we molecularly investigated equine blood samples (320 horses and 109 donkeys from Egypt) and four adult worms isolated from the peritoneal cavity of 5 out of the 94 slaughtered donkeys. In addition, quantitative enzyme-linked immunoassays (ELISAs) targeting circulating cytokines were used to identify whether the immunological profile of the infected animals is a Th1 (i.e., INF-gamma as indicator) or Th2 (i.e., IL-5 and IL-10 as indicators) response type. Overall, 13.8% and 0.3% of the donkeys and horses, respectively, were scored as positive for filaroid DNA. The 18S phylogeny revealed the occurrence of three different filaroid species, identified here as

Indexed as

cytokinesDirofilaria repensequidsMansonella sp.phylogenySetaria digitatazoonotic filariosis

Identifiers

PMID36145411
PMCPMC9501446
OpenAlexW4293769800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.