Evidence map›Paper›PMID 36145355›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

New Sulfamethoxazole Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors: Design, Synthesis, Cytotoxic Activity and Molecular Modeling.

Mohamed A Abdelgawad, Syed N A Bukhari, Arafa Musa, Mohammed Elmowafy, Mohammed H Elkomy, AbdElAziz A Nayl, Ahmed H El-Ghorab, Ibrahim Hotan Alsohaimi, Mohamed Sadek Abdel-Bakky, Ibrahim O Althobaiti and 6 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 3 countries.

Mohamed A AbdelgawadDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka 72431, Saudi Arabia.ORCID 0000-0001-9035-5638
Syed N A BukhariDepartment of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka 72431, Saudi Arabia.ORCID 0000-0001-8125-7972
Arafa MusaDepartment of Pharmacognosy, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.ORCID 0000-0003-0979-556X
Mohammed ElmowafyDepartment of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.ORCID 0000-0002-2393-8195
Mohammed H ElkomyDepartment of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.ORCID 0000-0003-4083-6024
AbdElAziz A NaylDepartment of Chemistry, College of Science, Jouf University, Sakaka 72341, Saudi Arabia.ORCID 0000-0003-0531-5194
Ahmed H El-GhorabDepartment of Chemistry, College of Science, Jouf University, Sakaka 72341, Saudi Arabia.
Ibrahim Hotan AlsohaimiDepartment of Chemistry, College of Science, Jouf University, Sakaka 72341, Saudi Arabia.ORCID 0000-0002-6312-0021
Mohamed Sadek Abdel-BakkyDepartment of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-0426-5458
Ibrahim O AlthobaitiDepartment of Chemistry, College of Science and Arts, Jouf University, Sakaka 72341, Saudi Arabia.
Hamud A AltalebDepartment of Chemistry, Faculty of Science, Islamic University of Madinah, Madinah 41477, Saudi Arabia.ORCID 0000-0001-5115-3179
Hany A OmarCollege of Pharmacy, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.ORCID 0000-0002-4670-8149
Ahmed H AbdelazeemDepartment of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.ORCID 0000-0002-0599-3393
Mohamed A ZakiPharmacognosy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.
Mohamed E ShakerDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72341, Saudi Arabia.
Heba A H ElshemyPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.
Jouf University · SABeni-Suef University · EGIslamic University of Madinah · SAQassim University · SAUniversity of Sharjah · AE

Funding

Div. of Clinical and Population-based Studies SpecialsU09RG000147 · RG · U.S. PHS PUBLIC ADVISORY GROUPS · PI HUMMER, ROBERT A · 2004 to 2005
$4.7M
CSR NIH HHS U09 RG000147This work was funded by the Deanship of Scientific Research at Jouf University under grant No Research Group (DSR-2022-RG-0147). DSR-2022-RG-0147
6 · The paper itself

Abstract

In this study new sulphamethoxazole derivatives (

Indexed as

anticancerapoptosiscarbonic anhydrasemolecular dockingsulfamethoxazole

Identifiers

PMID36145355
PMCPMC9501356
OpenAlexW4296011024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.