Evidence map›Paper›PMID 36145315›Full record

ReviewPharmaceuticals (Basel, Switzerland)2022

Importance of Rose Bengal Loaded with Nanoparticles for Anti-Cancer Photodynamic Therapy.

Batoul Dhaini, Laurène Wagner, Morgane Moinard, Joël Daouk, Philippe Arnoux, Hervé Schohn, Perrine Schneller, Samir Acherar, Tayssir Hamieh, Céline Frochot

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Photodynamic Therapy for Toxoplasma gondii Infections Using Rose Bengal.Luminescence : the journal of biological and chemical luminescence · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Batoul DhainiReactions and Chemical Engineering Laboratory, Université de Lorraine, LRGP-CNRS, F-54000 Nancy, France.ORCID 0000-0003-0372-2159
Laurène WagnerLaboratory of Macromolecular Physical Chemistry, Université de Lorraine, LCPM-CNRS, F-54000 Nancy, France.ORCID 0000-0002-3753-5805
Morgane MoinardReactions and Chemical Engineering Laboratory, Université de Lorraine, LRGP-CNRS, F-54000 Nancy, France.ORCID 0000-0002-2949-9146
Joël DaoukDepartment of Biology, Signals and Systems in Cancer and Neuroscience, Université de Lorraine, CRAN-CNRS, F-54000 Nancy, France.ORCID 0000-0001-8042-1726
Philippe ArnouxReactions and Chemical Engineering Laboratory, Université de Lorraine, LRGP-CNRS, F-54000 Nancy, France.ORCID 0000-0002-6834-9597
Hervé SchohnDepartment of Biology, Signals and Systems in Cancer and Neuroscience, Université de Lorraine, CRAN-CNRS, F-54000 Nancy, France.ORCID 0000-0002-3651-2636
Perrine SchnellerDepartment of Biology, Signals and Systems in Cancer and Neuroscience, Université de Lorraine, CRAN-CNRS, F-54000 Nancy, France.
Samir AcherarLaboratory of Macromolecular Physical Chemistry, Université de Lorraine, LCPM-CNRS, F-54000 Nancy, France.ORCID 0000-0002-8776-1632
Tayssir HamiehFaculty of Science and Engineering, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands.ORCID 0000-0003-2153-7408
Céline FrochotReactions and Chemical Engineering Laboratory, Université de Lorraine, LRGP-CNRS, F-54000 Nancy, France.ORCID 0000-0002-7659-3864

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rose Bengal (RB) is a photosensitizer (PS) used in anti-cancer and anti-bacterial photodynamic therapy (PDT). The specific excitation of this PS allows the production of singlet oxygen and oxygen reactive species that kill bacteria and tumor cells. In this review, we summarize the history of the use of RB as a PS coupled by chemical or physical means to nanoparticles (NPs). The studies are divided into PDT and PDT excited by X-rays (X-PDT), and subdivided on the basis of NP type. On the basis of the papers examined, it can be noted that RB used as a PS shows remarkable cytotoxicity under the effect of light, and RB loaded onto NPs is an excellent candidate for nanomedical applications in PDT and X-PDT.

Indexed as

cancernanomedicinenanoparticlephotodynamic therapyrose bengalsinglet oxygenX-rays

Identifiers

PMID36145315
PMCPMC9504923

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.