Evidence map›Paper›PMID 36145286›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Real-World Use of Molnupiravir in the Treatment of Outpatients with SARS-CoV-2 Infection-A Patient Profile Based on the Experience of a Tertiary Infectious Disease Center.

Anca Streinu-Cercel, Victor Daniel Miron, Alina Alexandra Oană, Mădălina Irimia, Ramona Ștefania Popescu, Ioana Andreea Dărămuș, Maria Magdalena Moțoi, Gabriela Jana Ceapraga, Oana Săndulescu

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Anca Streinu-CercelCarol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Victor Daniel MironCarol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-2318-5365
Alina Alexandra OanăCarol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Mădălina IrimiaCarol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Ramona Ștefania PopescuCarol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Ioana Andreea DărămușCarol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Maria Magdalena MoțoiCarol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Gabriela Jana CeapragaCarol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Oana SăndulescuCarol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-2586-4070
Carol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the current pandemic, the gap between fundamental research and clinical practice has been narrowing at a faster pace than ever before. While clinical trials play the main role of confirming the safety and efficacy of new drugs, a drug's introduction into clinical practice creates the need for further research in order to best position the use of the novel drug in terms of when, to whom, and how it would be best administered to achieve the best possible outcome under feasible clinical circumstances. We briefly present the results of a retrospective analysis of the characteristics of outpatients treated with molnupiravir in a tertiary care infectious disease hospital in Bucharest, Romania, between February and March 2022, when Romania was experiencing its fifth wave of COVID-19. A total of 46 outpatients received molnupiravir treatment and had complete clinical data available; of them, 56.5% (

Indexed as

antiviralCOVID-19molnupiravirreal-world dataSARS-CoV-2

Identifiers

PMID36145286
PMCPMC9502524
OpenAlexW4293769511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.