Evidence map›Paper›PMID 36145234›Full record

ArticleNutrients2022

Impact of Blueberry Consumption on the Human Fecal Bileacidome: A Pilot Study of Bile Acid Modulation by Freeze-Dried Blueberry.

William Gagnon, Véronique Garneau, Jocelyn Trottier, Mélanie Verreault, Charles Couillard, Denis Roy, André Marette, Jean-Philippe Drouin-Chartier, Marie-Claude Vohl, Olivier Barbier

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

William GagnonLaboratory of Molecular Pharmacology, Endocrinology and Nephrology Axis, CHU de Québec-Université Laval Research Center, Quebec City, QC G1V 4G2, Canada.
Véronique GarneauInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec City, QC G1V 0A6, Canada.
Jocelyn TrottierLaboratory of Molecular Pharmacology, Endocrinology and Nephrology Axis, CHU de Québec-Université Laval Research Center, Quebec City, QC G1V 4G2, Canada.
Mélanie VerreaultLaboratory of Molecular Pharmacology, Endocrinology and Nephrology Axis, CHU de Québec-Université Laval Research Center, Quebec City, QC G1V 4G2, Canada.
Charles CouillardInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec City, QC G1V 0A6, Canada.ORCID 0000-0002-6281-8663
Denis RoyInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec City, QC G1V 0A6, Canada.ORCID 0000-0002-4229-9245
André MaretteInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec City, QC G1V 0A6, Canada.ORCID 0000-0003-3950-5973
Jean-Philippe Drouin-ChartierFaculty of Pharmacy, Université Laval, Quebec City, QC G1V 0A6, Canada.ORCID 0000-0002-6733-4801
Marie-Claude VohlInstitute of Nutrition and Functional Foods (INAF), Université Laval, Quebec City, QC G1V 0A6, Canada.ORCID 0000-0002-7017-5848
Olivier BarbierLaboratory of Molecular Pharmacology, Endocrinology and Nephrology Axis, CHU de Québec-Université Laval Research Center, Quebec City, QC G1V 4G2, Canada.ORCID 0000-0002-3067-1134
Université Laval · CAMontreal Heart Institute · CA

Funding

Canadian Foundation for Innovation 17745CIHR PJT-175310NUTRISS research center - Université Laval NAUS Highbush Blueberry Council (USHBC) NA
6 · The paper itself

Abstract

Cholesterol-derived bile acids (BAs) affect numerous physiological functions such as glucose homeostasis, lipid metabolism and absorption, intestinal inflammation and immunity, as well as intestinal microbiota diversity. Diet influences the composition of the BA pool. In the present study, we analyzed the impact of a dietary supplementation with a freeze-dried blueberry powder (BBP) on the fecal BA pool composition. The diet of 11 men and 13 women at risk of metabolic syndrome was supplemented with 50 g/day of BBP for 8 weeks, and feces were harvested before (pre) and after (post) BBP consumption. BAs were profiled using liquid chromatography coupled with tandem mass spectrometry. No significant changes in total BAs were detected when comparing pre- vs. post-BBP consumption samples. However, post-BBP consumption samples exhibited significant accumulations of glycine-conjugated BAs (

Indexed as

Bile Acids and SaltsBlueberry PlantsCholic AcidFecesFemaleGlucoseGlycineHumansMalePilot ProjectsPowdersBile Acids and SaltsCholic AcidGlucoseGlycinePowdersbile acidsblueberriesdietary supplementsLC-MS/MS profilingpolyphenols

Identifiers

PMID36145234
PMCPMC9501813
OpenAlexW4296365669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.