Evidence map›Paper›PMID 36145223›Full record

Observational studyNutrients2022

Nutritional Predictors of Mortality after 10 Years of Follow-Up in Patients with Chronic Kidney Disease at a Multidisciplinary Unit of Advanced Chronic Kidney Disease.

Guillermina Barril, Angel Nogueira, Graciela Alvarez-García, Almudena Núñez, Carmen Sánchez-González, Mar Ruperto

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Guillermina BarrilAdvanced Chronic Kidney Disease Unit, Department of Nephrology, Hospital Universitario de la Princesa, C/Diego de León 62, 28006 Madrid, Spain.ORCID 0000-0003-4067-634X
Angel NogueiraAdvanced Chronic Kidney Disease Unit, Department of Nephrology, Hospital Universitario de la Princesa, C/Diego de León 62, 28006 Madrid, Spain.
Graciela Alvarez-GarcíaAdvanced Chronic Kidney Disease Unit, Department of Nephrology, Hospital Universitario de la Princesa, C/Diego de León 62, 28006 Madrid, Spain.
Almudena NúñezAdvanced Chronic Kidney Disease Unit, Department of Nephrology, Hospital Universitario de la Princesa, C/Diego de León 62, 28006 Madrid, Spain.
Carmen Sánchez-GonzálezAdvanced Chronic Kidney Disease Unit, Department of Nephrology, Hospital Universitario de la Princesa, C/Diego de León 62, 28006 Madrid, Spain.
Mar RupertoDepartment of Pharmaceutical & Health Sciences, School of Pharmacy, Universidad San Pablo-CEU, CEU Universities, Urbanización Monteprincipe, 28660 Madrid, Spain.ORCID 0000-0002-8790-4007
Hospital Universitario de La Princesa · ESUniversidad San Pablo CEU · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutritional monitoring in advanced chronic kidney disease (ACKD) units provides personalized care and improves clinical outcomes. This study aimed to identify mortality risk factors in chronic kidney disease (CKD) patients on nutritional follow-up in the multidisciplinary ACKD unit. A retrospective cross-sectional observational study was conducted in 307 CKD patients’ stage 3b, 4−5 followed-up for 10 years. Clinical and nutritional monitoring was performed by malnutrition-inflammation score (MIS), biochemical parameters (s-albumin, s-prealbumin, and serum C-reactive protein (s-CRP), body composition measured by bioelectrical impedance analysis (BIA), anthropometry, and handgrip strength measurements. The sample was classified into non-survivors, survivors, and censored groups. Of the 307 CKD patients, the prevalence of protein-energy wasting (PEW) was 27.0% using MIS > 5 points, s-CRP > 1 mg/dL was 19.20%, and 27.18% died. Survivors had higher significant body cell mass (BCM%) and phase angle (PA). Survival analyses significantly showed that age > 72 years, MIS > 5 points, s-prealbumin ≤ 30 mg/dL, PA ≤ 4°, and gender-adjusted handgrip strength (HGS) were associated with an increased risk of mortality. By univariate and multivariate Cox regression, time on follow-up (HR:0.97), s-prealbumin (HR:0.94), and right handgrip strength (HR:0.96) were independent predictors of mortality risk at 10 years of follow-up in the ACKD unit. Nutritional monitoring in patients with stage 3b, 4−5 CKD helps to identify and treat nutritional risk early and improve adverse mortality prognosis.

Indexed as

MalnutritionRenal Insufficiency, ChronicAgedBody CompositionC-Reactive ProteinCross-Sectional StudiesElectric ImpedanceFollow-Up StudiesHand StrengthHumansInflammationNutritional StatusPrealbuminRetrospective StudiesC-Reactive ProteinPrealbuminACKD unitadvanced chronic kidney disease unitbioelectric impedance analysisbody compositionchronic kidney diseasefluid overloadhandgrip strengthmortalitynutritional follow-upprotein-energy wasting

Identifiers

PMID36145223
PMCPMC9504469
OpenAlexW4296365642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.