Evidence map›Paper›PMID 36145200›Full record

ArticleNutrients2022

Mendelian Randomization Analysis of the Association of SOCS3 Methylation with Abdominal Obesity.

Yuqian Li, Xiaotian Liu, Runqi Tu, Jian Hou, Guihua Zhuang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yuqian LiDepartmentof Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Centre, Xi'an 710061, China.
Xiaotian LiuDepartment of Epidemiology and Biostatistics, School of Public Health, Zhengzhou University, Zhengzhou 450052, China.
Runqi TuDepartment of Epidemiology and Biostatistics, School of Public Health, Zhengzhou University, Zhengzhou 450052, China.
Jian HouDepartment of Epidemiology and Biostatistics, School of Public Health, Zhengzhou University, Zhengzhou 450052, China.
Guihua ZhuangDepartmentof Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Centre, Xi'an 710061, China.
Zhengzhou University · CNXi'an Jiaotong University · CN

Funding

Foundation of National Key Program of Research and Development of China 2016YFC0900803National Natural Science Foundation of China 81602925, 82003543Science and Technology Innovation Team Support Plan of Colleges and Universities in Henan Province 21IRTSTHN029
6 · The paper itself

Abstract

This study was conducted to evaluate the potential causality association of SOCS3 methylation with abdominal obesity using Mendelian randomization. A case-control study, including 1064 participants, was carried out on Chinese subjects aged 18 to 79. MethylTargetTM was used to detect the methylation level for each CpG site of SOCS3, and SNPscan

Indexed as

Mendelian Randomization AnalysisObesity, AbdominalCase-Control StudiesDNA MethylationGenome-Wide Association StudyHumansObesityPolymorphism, Single NucleotideSuppressor of Cytokine Signaling 3 ProteinSOCS3 protein, humanSuppressor of Cytokine Signaling 3 Proteinabdominal obesityMendelian randomizationmethylationsingle-nucleotide polymorphismSOCS3

Identifiers

PMID36145200
PMCPMC9503364
OpenAlexW4296456081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.