Evidence map›Paper›PMID 36145154›Full record

ArticleNutrients2022

Could the Majority of the Greek and Cypriot Population Be Vitamin D Deficient?

Souzana E Xyda, Kalliopi Kotsa, Argyrios Doumas, Emmanouil Papanastasiou, Alexandros A Garyfallos, George Samoutis

Abstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Souzana E XydaMedical School Department, Faculty of Medical Sciences, University College London, Gower Street, London WC1E 6BT, UK.
Kalliopi KotsaDivision of Endocrinology and Metabolism, 1st Department of Internal Medicine, AHEPA Hospital, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-2376-740X
Argyrios DoumasDepartment of Radiology and Medical Informatics, AHEPA Hospital, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Emmanouil PapanastasiouLaboratory of Medical Physics and Digital Innovation, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-8497-6849
Alexandros A Garyfallos4th Department of Internal Medicine, Hippokration University Hospital, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
George SamoutisDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia 2408, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHypovitaminosis D is prevalent in epidemic proportions in many developed countries. The aim of this study is to investigate the prevalence of adequate 25-hydroxyvitamin D [25(OH)D] levels in two Mediterranean countries, Greece and Cyprus.

methodsData such as 25(OH)D, the month of blood sample collection, and demographic information were blindly collected from 8780 Greek and 2594 Cypriot individuals over 5 years. Comorbidities were also recorded for 839 Greek subjects. Univariate and multivariate analyses were used to examine the relationship between these variables and 25(OH)D levels.

resultsIn the samples studied, 72.7% of the Greek and 69.3% of the Cypriot population sample had inadequate levels of 25(OH)D. The mean level for the Greek subjects was 25.1 ng/mL and for Cypriots 25.8 ng/mL. For both samples, only month and gender were significantly associated with 25(OH)D levels, and the highest mean levels were recorded in September. For the recorded diseases, the lowest levels were recorded in sickle cell anaemia 13.6 ± 10.2 ng/mL, autoimmune diseases 13.0 ± 8.4 ng/mL, and cancer 22.6 ± 9.5 ng/mL.

conclusionsThe prevalence of vitamin D deficiency is paradoxically high in both Mediterranean countries.

Indexed as

Vitamin D DeficiencyCalcifediolGreeceHumansPrevalenceVitamin DCalcifediolVitamin DcholecalciferolCyprusGreecevitamin Dvitamin D deficiencyvitamin D insufficiencyvitamin D status

Identifiers

PMID36145154
PMCPMC9502779

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.