Evidence map›Paper›PMID 36145125›Full record

ReviewNutrients2022

Correlation between Olive Oil Intake and Gut Microbiota in Colorectal Cancer Prevention.

Raffaella Memmola, Angelica Petrillo, Sara Di Lorenzo, Sara C Altuna, Baker Shalal Habeeb, Alessio Soggiu, Luigi Bonizzi, Ornella Garrone, Michele Ghidini

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Raffaella MemmolaDepartment of Biochemical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.
Angelica PetrilloMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.
Sara Di LorenzoMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.
Sara C AltunaMedical Oncology, Oncomedica C.A., Caracas 1060, Venezuela.
Baker Shalal HabeebOncology Department, Shaqlawa Teaching Hospital, Shaqlawa City 44005, Iraq.ORCID 0000-0001-8070-8532
Alessio SoggiuDepartment of Biochemical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.ORCID 0000-0001-7680-6068
Luigi BonizziDepartment of Biochemical, Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy.
Ornella GarroneOncology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20131 Milan, Italy.ORCID 0000-0001-7359-5410
Michele GhidiniOncology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20131 Milan, Italy.ORCID 0000-0001-5435-1218
University of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

Ministero della Salute Grant Ricerca Corrente 2021
6 · The paper itself

Abstract

Extra virgin olive oil (EVOO) is a mainstay of the Mediterranean diet with its excellent balance of fats and antioxidant bioactive compounds. Both the phenolic and lipid fractions of EVOO contain a variety of antioxidant and anticancer substances which might protect from the development of colorectal cancer (CRC). The function of the intestinal microbiome is essential for the integrity of the intestinal epithelium, being protective against pathogens and maintaining immunity. Indeed, dysbiosis of the microbiota alters the physiological functions of the organ, leading to the onset of different diseases including CRC. It is known that some factors, including diet, could deeply influence and modulate the colon microenvironment. Although coming from animal models, there is increasing evidence that a diet rich in EVOO is linked to a significant reduction in the diversity of gut microbiome (GM), causing a switch from predominant bacteria to a more protective group of bacteria. The potential beneficial effect of the EVOO compounds in the carcinogenesis of CRC is only partially known and further trials are needed in order to clarify this issue. With this narrative review, we aim at discussing the available evidence on the effect of olive oil consumption on GM in the prevention of CRC.

Indexed as

Colorectal NeoplasmsDiet, MediterraneanGastrointestinal MicrobiomeAnimalsAntioxidantsOlive OilTumor MicroenvironmentAntioxidantsOlive Oilantioxidantscolorectal cancerEVOOextra virgin olive oilmicrobiotaolive oil

Identifiers

PMID36145125
PMCPMC9504660
OpenAlexW4296588607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.