Evidence map›Paper›PMID 36144948›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Microfluidic Synthesis of -NH

Cristina Chircov, Alexandra Cătălina Bîrcă, Bogdan Stefan Vasile, Ovidiu-Cristian Oprea, Keng-Shiang Huang, Alexandru Mihai Grumezescu

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. New 3D Spiral Microfluidic Platform Tested for FeMolecules (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Zinc/Cerium-Substituted Magnetite Nanoparticles for Biomedical Applications.International journal of molecular sciences · 2023
    Article
  6. Article
  7. MAPLE Processed Nanostructures for Antimicrobial Coatings.International journal of molecular sciences · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristina ChircovDepartment of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania.ORCID 0000-0002-8695-6884
Alexandra Cătălina BîrcăDepartment of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania.
Bogdan Stefan VasileDepartment of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania.ORCID 0000-0002-2267-6453
Ovidiu-Cristian OpreaNational Research Center for Micro and Nanomaterials, University Politehnica of Bucharest, 060042 Bucharest, Romania.ORCID 0000-0002-8145-1094
Keng-Shiang HuangThe School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung 840301, Taiwan.ORCID 0000-0002-7751-0223
Alexandru Mihai GrumezescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania.ORCID 0000-0003-3036-094X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microfluidics has emerged as a promising alternative for the synthesis of nanoparticles, which ensures precise control over the synthesis parameters, high uniformity, reproducibility, and ease of integration. Therefore, the present study investigated a one-step synthesis and functionalization of magnetite nanoparticles (MNPs) using sulfanilic acid (SA) and 4-sulfobenzoic acid (SBA). The flows of both the precursor and precipitating/functionalization solutions were varied in order to ensure the optimal parameters. The obtained nanoparticles were characterized through dynamic light scattering (DLS) and zeta potential, X-ray diffraction (XRD), selected area electron diffraction (SAED), transmission electron microscopy (TEM) and high-resolution TEM (HR-TEM), Fourier transform infrared spectroscopy (FT-IR), thermogravimetry and differential scanning calorimetry (TG-DSC), and vibrating sample magnetometry (VSM). The results demonstrated the successful synthesis of magnetite as the unique mineralogical phase, as well as the functionalization of the nanoparticles. Furthermore, the possibility to control the crystallinity, size, shape, and functionalization degree by varying the synthesis parameters was further confirmed. In this manner, this study validated the potential of the microfluidic platform to develop functionalized MNPs, which are suitable for biomedical and pharmaceutical applications.

Indexed as

aminocarboxyllab-on-chipmagnetite nanoparticlesmicrofluidicsnanoparticle functionalization

Identifiers

PMID36144948
PMCPMC9503789

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.