Evidence map›Paper›PMID 36144856›Full record

ArticleMolecules (Basel, Switzerland)2022

Novel 4-Azapregnene Derivatives as Potential Anticancer Agents: Synthesis, Antiproliferative Activity and Molecular Docking Studies.

Vanessa Brito, Adriana Oliveira Santos, Gilberto Alves, Paulo Almeida, Samuel Silvestre

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vanessa BritoHealth Sciences Research Centre (CICS-UBI), Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0002-8030-9379
Adriana Oliveira SantosHealth Sciences Research Centre (CICS-UBI), Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.
Gilberto AlvesHealth Sciences Research Centre (CICS-UBI), Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0002-4213-0714
Paulo AlmeidaHealth Sciences Research Centre (CICS-UBI), Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0003-0110-4795
Samuel SilvestreHealth Sciences Research Centre (CICS-UBI), Universidade da Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0003-4297-5108
University of Beira Interior · PT

Funding

BID/ICI-FC/Santander Universidades-UBI/2016 BID/ICI-FC/Santander Universidades-UBI/2016C4-Cloud Computing Competences Center CENTRO-01-0145-FEDER-000019FEDER funds through the POCI - COMPETE 2020 - Operational Programme Competitiveness and Internationalization in Axis I - Strengthening Research, Technological Development and Innovation Project No. 007491FEDER through COMPETE 2020, POCI and PORL and FCT through PIDDAC Project No. 022161Foundation for Science and Technology Project UID/ Multi/00709Fundação para a Ciência e Tecnologia SFRH/BD/131059/ 2017
6 · The paper itself

Abstract

A series of novel 21

Indexed as

Antineoplastic AgentsReceptors, AndrogenAndrogensAzasteroidsCell Line, TumorCell ProliferationCholestenone 5 alpha-ReductaseDrug Screening Assays, AntitumorEstrogen Receptor alphaMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAndrogensAntineoplastic AgentsAzasteroidsCholestenone 5 alpha-ReductaseEstrogen Receptor alphaReceptors, Androgen4-azapregnenes4-azasteroidsaldol condensationantiproliferative activitymolecular docking

Identifiers

PMID36144856
PMCPMC9501232
OpenAlexW4296742284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.