ArticleMolecules (Basel, Switzerland)2022
Effect of Plant Bioactive Compounds Supplemented in Transition Dairy Cows on the Metabolic and Inflammatory Status.
Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The trial behind it
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Who cites it
7 citing papers in PubMed, 5 citations in OpenAlex.
- Effects of OralAnimals : an open access journal from MDPI · 2026Article
- FeedingVeterinary and animal science · 2026Article
- Enhancing lactation performance and energy utilisation efficiency through dietary inclusion of apple pomace silage and hempseed cake in dairy cows.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Inflammation-Associated Changes in Bioactive Proteins and Peptides of Bovine Milk: Evidence from Mastitis, Lameness, and Metabolic Disorders-A Review.Molecules (Basel, Switzerland) · 2026Review
- Effects of Myrtus (Animals : an open access journal from MDPI · 2026Article
- Multi-omics analysis reveals the mechanism of rosemary extract supplementation in increasing milk production in Sanhe dairy cows via the "rumen-serum-milk" metabolic pathway.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Plasma and Milk Variables Classify Diet, Dry Period Length, and Lactation Week of Dairy Cows Using a Machine Learning Approach.Metabolites · 2025Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
(1) Background: This study evaluated the effects of a plant bioactive (Phyto Ax’Cell, Phytosynthese, Mozac, France) on the inflammatory status and health of dairy cows during calving. (2) Methods: 46 Holstein crossbred cows were randomized into a control group (CON, n = 23) and the Phyto Ax’Cell group (PAC, n = 23). PAC received Phyto Ax’Cell at 25 g/cow/day, from 15 days prepartum to 7 days postpartum. Blood analyses were performed weekly from D-7 to D14 to evaluate the energy metabolism and inflammatory status; rectal temperature was measured daily within 14 days from calving day (D0). (3) Results: PAC showed lower serum haptoglobin at D7 (0.55 vs. 0.79 mg/mL; p < 0.05) and D14 (0.44 vs. 0.66 mg/mL; p < 0.05). CON had a higher number of circulating white blood cells and granulocytes on D7 (p < 0.05). Fewer cows from PAC showed hyperthermia (≥39 °C) during the first 2 weeks postpartum (−7%, p < 0.05). Energy metabolism, which was represented by the NEFA/cholesterol ratio, improved (0.21 vs. 0.36 at D0, p < 0.1; 0.19 and 0.15 vs. 0.36 and 0.32, respectively, at D+7 and D+14, p < 0.05) under the plant bioactive supplementation. (4) Conclusions: The results suggest that the anti-inflammatory plant bioactive compound with Brazilian green propolis administered during calving had a beneficial effect on the energy and inflammatory status of dairy cows.
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Registered trials
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