Evidence map›Paper›PMID 36144671›Full record

ArticleMolecules (Basel, Switzerland)2022

Extraction of Bioactive Compounds for Antioxidant, Antimicrobial, and Antidiabetic Applications.

Fatimah Saeed Aldughaylibi, Muhammad Asam Raza, Sumaira Naeem, Humera Rafi, Mir Waqas Alam, Basma Souayeh, Mohd Farhan, Muhammad Aamir, Noushi Zaidi, Tanveer Ahmad Mir

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Saudi journal of biological sciences · 2024
    Article
  7. Article
  8. Identification of Compounds ofPharmaceuticals (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Bioassay-Guided Alkaloids Isolation fromMolecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fatimah Saeed AldughaylibiDepartment of Physics, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Muhammad Asam RazaDepartment of Chemistry, University of Gujrat, Gujrat 50700, Pakistan.ORCID 0000-0002-6723-2637
Sumaira NaeemDepartment of Chemistry, University of Gujrat, Gujrat 50700, Pakistan.
Humera RafiDepartment of Chemistry, University of Gujrat, Gujrat 50700, Pakistan.
Mir Waqas AlamDepartment of Physics, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0001-5190-0103
Basma SouayehDepartment of Physics, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0003-3631-4071
Mohd FarhanDepartment of Basic Sciences, Preparatory Year Deanship, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-1519-9644
Muhammad AamirDepartment of Basic Sciences, Preparatory Year Deanship, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Noushi ZaidiDepartment of Basic Sciences, Preparatory Year Deanship, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Tanveer Ahmad MirLaboratory of Tissue/Organ Bioengineering and BioMEMS, Organ Transplant Centre of Excellence, Transplantation Research & Innovation (Dpt)-R, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, Saudi Arabia.ORCID 0000-0002-0093-0924

Funding

This work was supported by Al Bilad Bank Scholarly Chair for Food Security in Saudi Arabia: the Deanship of Scientific Research, Vice Presidency for Graduate Studies and Scientific Research, King Faisal University, Saudi Arabia [Project No. CHAIR38].
6 · The paper itself

Abstract

This study was designed to check the potential of secondary metabolites of the selected plants; Citrullus colocynthis, Solanum nigrum, Solanum surattense, Calotropis procera, Agave americana, and Anagallis arvensis for antioxidant, antibacterial, antifungal, and antidiabetic agents. Plant material was soaked in ethanol/methanol to get the crude extract, which was further partitioned via solvent extraction technique. GCMS and FTIR analytical techniques were applied to check the compounds responsible for causing antioxidant, antimicrobial, and antidiabetic activities. It was concluded that about 80% of studied extracts/fractions were active against α-amylase, ranging from 43 to 96%. The highest activity (96.63%) was exhibited by butanol fractions of A. arvensis while the least response (43.65%) was shown by the aqueous fraction of C. colocynthis and the methanol fraction of fruit of S. surattense. The highest antioxidant activity was shown by the ethyl acetate fraction of Anagallis arvensis (78.1%), while aqueous as well as n-hexane fractions are the least active throughout the assay. Results showed that all tested plants can be an excellent source of natural products with potential antimicrobial, antioxidant, and antidiabetic potential. The biological response of these species is depicted as a good therapeutic agent, and, in the future, it can be encapsulated for drug discovery.

Indexed as

Anti-Infective AgentsAntioxidantsalpha-AmylasesAnti-Bacterial AgentsAntifungal AgentsButanolsEthanolHypoglycemic AgentsMethanolPlant ExtractsSolventsalpha-AmylasesAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsAntioxidantsButanolsEthanolHypoglycemic AgentsMethanolPlant ExtractsSolventsantidiabeticantimicrobialantioxidantGC-MSmedicinal plants

Identifiers

PMID36144671
PMCPMC9503716

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.