Evidence map›Paper›PMID 36144637›Full record

ArticleMolecules (Basel, Switzerland)2022

Sweroside Ameliorated Memory Deficits in Scopolamine-Induced Zebrafish (

Ion Brinza, Mohamed A El Raey, Walaa El-Kashak, Omayma A Eldahshan, Lucian Hritcu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Extract fromNutrients · 2024
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  5. The Effect of aPharmaceuticals (Basel, Switzerland) · 2024
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  7. Direct Evidence for UsingAntioxidants (Basel, Switzerland) · 2023
    Article
  8. Molecules (Basel, Switzerland) · 2023
    Review
  9. Review
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ion BrinzaDepartment of Biology, Faculty of Biology, Alexandru Ioan Cuza University of Iasi, Bd. Carol I, No. 11, 700505 Iasi, Romania.ORCID 0000-0003-3103-9728
Mohamed A El RaeyDepartment of Phytochemistry and Plant Systematics, National Research Centre, Dokki, Cairo 12622, Egypt.ORCID 0000-0002-5960-3012
Walaa El-KashakDepartment of Chemistry of Natural Compounds, National Research Centre, Dokki, Cairo 12622, Egypt.
Omayma A EldahshanDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo 11566, Egypt.ORCID 0000-0002-0972-0560
Lucian HritcuDepartment of Biology, Faculty of Biology, Alexandru Ioan Cuza University of Iasi, Bd. Carol I, No. 11, 700505 Iasi, Romania.ORCID 0000-0001-6981-4174
Alexandru Ioan Cuza University · RONational Research Centre · EGAin Shams University · EG

Funding

This research received funding from the Doctoral School of Biology, Alexandru Ioan Cuza Uni-versity of Iasi, Romania. 0
6 · The paper itself

Abstract

Sweroside is a secoiridoid glycoside and belongs to a large group of naturally occurring monoterpenes with glucose sugar attached to C-1 in the pyran ring. Sweroside can promote different biological activities such as antifungal, antibacterial, hepatoprotective, gastroprotective, sedative and antitumor, antioxidant, and neuroprotective activities. Zebrafish were given sweroside (12.79, 8.35, and 13.95 nM) by immersion once daily for 8 days, along with scopolamine (Sco, 100 μM) 30 min before the initiation of the behavioral testing to cause anxiety and memory loss. Employing the novel tank diving test (NTT), the Y-maze, and the novel object recognition test (NOR), anxiety-like reactions and memory-related behaviors were assessed. The following seven groups (

Indexed as

ScopolamineZebrafishAcetylcholinesteraseAnimalsAnti-Bacterial AgentsAntifungal AgentsAntioxidantsBrainCholinergic AgentsGalantamineGlucoseHypnotics and SedativesImipramineIridoid GlucosidesMaze LearningMemory DisordersAcetylcholinesteraseAnti-Bacterial AgentsAntifungal AgentsAntioxidantsCholinergic AgentsGalantamineGlucoseHypnotics and SedativesImipramineIridoid GlucosidesScopolamineSugarsswerosidecholinergic functionmemoryoxidative stressSchenkia spicatascopolamineswerosidezebrafish

Identifiers

PMID36144637
PMCPMC9502219
OpenAlexW4296014595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.