Evidence map›Paper›PMID 36144621›Full record

ReviewMolecules (Basel, Switzerland)2022

Cold-Active Enzymes and Their Potential Industrial Applications-A Review.

Burhan Hamid, Zaffar Bashir, Ali Mohd Yatoo, Fayaz Mohiddin, Neesa Majeed, Monika Bansal, Peter Poczai, Waleed Hassan Almalki, R Z Sayyed, Ali A Shati and 1 more

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Article
  3. Partial purification and characterization of an extracellular cold-active protease from Flavobacterium azizsancarii, a novel Antarctic isolate.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Cold-Active Lipase from the Ice CaveMolecules (Basel, Switzerland) · 2024
    Article
  17. Review
  18. Review
  19. Article
  20. The Impact of Metagenomics on Biocatalysis.Angewandte Chemie (International ed. in English) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Burhan HamidCentre of Research for Development, University of Kashmir, Srinagar 190006, India.ORCID 0000-0003-1630-9929
Zaffar BashirCentre of Research for Development, University of Kashmir, Srinagar 190006, India.
Ali Mohd YatooCentre of Research for Development, University of Kashmir, Srinagar 190006, India.ORCID 0000-0002-5094-5905
Fayaz MohiddinMountain Research Center for Field Crops, Khudwani, Sher-e-Kashmir University of Agricultural Sciences and Technology, Srinagar 190025, India.ORCID 0000-0001-9720-4429
Neesa MajeedCentre of Research for Development, University of Kashmir, Srinagar 190006, India.
Monika BansalSIILAS Campus, Jaipur National University, Jaipur 302025, India.
Peter PoczaiFinnish Museum of Natural History, University of Helsinki, FL10044 Helsinki, Finland.ORCID 0000-0002-0107-1068
Waleed Hassan AlmalkiDepartment of Pharmacology, College of Pharmacy, Umm Al Qura University, Makkah 77207, Saudi Arabia.
R Z SayyedDepartment of Microbiology, PSGVP Mandal's, S I Patil Arts, G B Patel Science & STKV Sangh Commerce College, Shahada 425409, India.ORCID 0000-0002-1553-1213
Ali A ShatiBiology Department, Faculty of Science, King Khalid University, Abha 9004, Saudi Arabia.
Mohammad Y AlfaifiBiology Department, Faculty of Science, King Khalid University, Abha 9004, Saudi Arabia.ORCID 0000-0003-4310-3539

Funding

Deanship of Scientific Research at Umm Al Qura University, Makkah, Saudi Arabia project code: 22UQU4310387DSR15
6 · The paper itself

Abstract

More than 70% of our planet is covered by extremely cold environments, nourishing a broad diversity of microbial life. Temperature is the most significant parameter that plays a key role in the distribution of microorganisms on our planet. Psychrophilic microorganisms are the most prominent inhabitants of the cold ecosystems, and they possess potential cold-active enzymes with diverse uses in the research and commercial sectors. Psychrophiles are modified to nurture, replicate, and retain their active metabolic activities in low temperatures. Their enzymes possess characteristics of maximal activity at low to adequate temperatures; this feature makes them more appealing and attractive in biotechnology. The high enzymatic activity of psychrozymes at low temperatures implies an important feature for energy saving. These enzymes have proven more advantageous than their mesophilic and thermophilic counterparts. Therefore, it is very important to explore the efficiency and utility of different psychrozymes in food processing, pharmaceuticals, brewing, bioremediation, and molecular biology. In this review, we focused on the properties of cold-active enzymes and their diverse uses in different industries and research areas. This review will provide insight into the areas and characteristics to be improved in cold-active enzymes so that potential and desired enzymes can be made available for commercial purposes.

Indexed as

Cold TemperatureEcosystemBiotechnologyEnzymesPharmaceutical PreparationsEnzymesPharmaceutical Preparationsbiotechnological potentialcold-active enzymesextremophilesindustrial applicationspsychrophiles

Identifiers

PMID36144621
PMCPMC9501442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.