Evidence map›Paper›PMID 36144597›Full record

ArticleMolecules (Basel, Switzerland)2022

Uncertainty Quantification and Sensitivity Analysis for the Electrical Impedance Spectroscopy of Changes to Intercellular Junctions Induced by Cold Atmospheric Plasma.

Jie Zhuang, Cheng Zhu, Rui Han, Anna Steuer, Juergen F Kolb, Fukun Shi

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jie ZhuangSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.ORCID 0000-0002-6136-9499
Cheng ZhuSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Rui HanSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Anna SteuerLeibniz Institute for Plasma Science and Technology (INP), 17489 Greifswald, Germany.
Juergen F KolbLeibniz Institute for Plasma Science and Technology (INP), 17489 Greifswald, Germany.ORCID 0000-0002-0434-5001
Fukun ShiSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
University of Science and Technology of China · CNLeibniz Institute for Plasma Science and Technology · DEChinese Academy of Sciences · CN

Funding

Basic Research Pilot Project of Suzhou SJC2021025the "Hundred Talents Program" of the "Pioneer Initiative" in Chinese Academy of Sciences Y722171202Top Young Scholar of National "Ten Thousands Talent Program" 1188006041
6 · The paper itself

Abstract

The influence of pertinent parameters of a Cole-Cole model in the impedimetric assessment of cell-monolayers was investigated with respect to the significance of their individual contribution. The analysis enables conclusions on characteristics, such as intercellular junctions. Especially cold atmospheric plasma (CAP) has been proven to influence intercellular junctions which may become a key factor in CAP-related biological effects. Therefore, the response of rat liver epithelial cells (WB-F344) and their malignant counterpart (WB-ras) was studied by electrical impedance spectroscopy (EIS). Cell monolayers before and after CAP treatment were analyzed. An uncertainty quantification (UQ) of Cole parameters revealed the frequency cut-off point between low and high frequency resistances. A sensitivity analysis (SA) showed that the Cole parameters,

Indexed as

Dielectric SpectroscopyPlasma GasesAnimalsElectric ImpedanceHydrogen PeroxideIntercellular JunctionsRatsRats, Inbred F344Reactive Oxygen SpeciesUncertaintyHydrogen PeroxidePlasma GasesReactive Oxygen Speciescold atmospheric plasmaCole-Cole modelintercellular junctionssensitivity analysisuncertainty quantification

Identifiers

PMID36144597
PMCPMC9503961
OpenAlexW4296016617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.