Evidence map›Paper›PMID 36144552›Full record

ArticleMolecules (Basel, Switzerland)2022

Production of Bioactive Peptides from Baltic Herring (

Sari Mäkinen, Jaakko Hiidenhovi, Xin Huang, Amanda Dos Santos Lima, Luciana Azevedo, Jari Setälä, Anna-Liisa Välimaa, Pirjo Mattila, Daniel Granato

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Sari MäkinenProduction Systems Unit-Natural Resources Institute Finland (Luke), FI-31600 Jokioinen, Finland.ORCID 0000-0002-7884-839X
Jaakko HiidenhoviProduction Systems Unit-Natural Resources Institute Finland (Luke), FI-31600 Jokioinen, Finland.ORCID 0000-0002-6525-7507
Xin HuangProduction Systems Unit-Natural Resources Institute Finland (Luke), FI-31600 Jokioinen, Finland.ORCID 0000-0003-0869-840X
Amanda Dos Santos LimaFaculty of Nutrition, Federal University of Alfenas, Rua Gabriel Monteiro da Silva, 714, Alfenas 37130-000, Brazil.ORCID 0000-0002-7919-8640
Luciana AzevedoFaculty of Nutrition, Federal University of Alfenas, Rua Gabriel Monteiro da Silva, 714, Alfenas 37130-000, Brazil.ORCID 0000-0002-0502-4090
Jari SetäläProduction Systems Unit-Natural Resources Institute Finland (Luke), FI-20520 Turku, Finland.
Anna-Liisa VälimaaProduction Systems Unit-Natural Resources Institute Finland (Luke), University of Oulu, FI-90014 Oulu, Finland.
Pirjo MattilaProduction Systems Unit-Natural Resources Institute Finland (Luke), FI-20520 Turku, Finland.
Daniel GranatoBioactivity and Applications Lab, Department of Biological Sciences, Faculty of Science and Engineering, University of Limerick, V94 T9PX Limerick, Ireland.ORCID 0000-0002-4533-1597
Natural Resources Institute Finland · FIUniversidade Federal de Alfenas · BRUniversity of Limerick · IE

Funding

Natural Resources Institute Finland NoVaProthe Finnish Operational Programme of the European Maritime and Fisheries Fund Project no. 33338
6 · The paper itself

Abstract

This study aimed to produce bioactive protein hydrolysates from undervalued fish, namely Baltic herring, and its filleting by-products. Protein hydrolysates were produced with Alcalase and Flavourzyme to achieve effective hydrolysis. The hydrolysates were evaluated for chemical composition, molecular weight distribution, antioxidant capacity, dipeptidyl-peptidase 4 (DPP4) inhibitory activity, effects on cell proliferation and surface hydrophobicity. The protein content of the hydrolysates was high, from 86% to 91% (dm), while the fat content was low, from 0.3% to 0.4% (dm). The hydrolysates showed high DPP4 inhibition activities with IC

Indexed as

Dipeptidyl Peptidase 4Protein HydrolysatesAnimalsAntioxidantsBlood GlucoseFishesHydrolysisPeptidesSubtilisinsAntioxidantsBlood GlucoseDipeptidyl Peptidase 4PeptidesProtein HydrolysatesSubtilisinsantidiabetic effectsantioxidantsbioactive peptidescell-based experimentsreactive oxygen species

Identifiers

PMID36144552
PMCPMC9500839
OpenAlexW4296117839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.