Evidence map›Paper›PMID 36144511›Full record

ArticleMolecules (Basel, Switzerland)2022

A Concise Synthesis of Sacidumlignan B.

Zhiyuan Zhuang, Zhenbiao Luo, Sichen Yao, Yawen Wang, Yu Peng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhiyuan ZhuangState Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China.
Zhenbiao LuoState Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China.
Sichen YaoSichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.
Yawen WangSichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.ORCID 0000-0003-2582-8886
Yu PengSichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.ORCID 0000-0002-3862-632X
Southwest Jiaotong University · CNLanzhou University · CN

Funding

National Natural Science Foundation of China 21772078 and 22071200
6 · The paper itself

Abstract

A short synthesis of racemic Sacidumlignan B was achieved for the first time. The key steps included a formal reductive coupling between the diaryl ketone and the crotyl bromide, and the subsequent Friedel-Crafts cyclization, which led to an efficient construction of dihydronaphthalene skeleton in this 2,7'-cyclolignan natural product.

Indexed as

Biological ProductsBromidesCyclizationKetonesLignansMolecular StructureBiological ProductsBromidesKetonesLignanssacidumlignan BBarbier reactioncyclizationcyclolignansynthetic efficiencytotal synthesis

Identifiers

PMID36144511
PMCPMC9500800
OpenAlexW4295007770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.