Evidence map›Paper›PMID 36144473›Full record

ArticleMicroorganisms2022

Pep27 Mutant Immunization Inhibits Caspase-14 Expression to Alleviate Inflammatory Bowel Disease via Treg Upregulation.

Hamid Iqbal, Gyu-Lee Kim, Ji-Hoon Kim, Prachetash Ghosh, Masaud Shah, Wonsik Lee, Dong-Kwon Rhee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hamid IqbalSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Gyu-Lee KimSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Ji-Hoon KimSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Prachetash GhoshSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Masaud ShahDepartment of Physiology, Ajou University, Suwon 16499, Korea.
Wonsik LeeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Dong-Kwon RheeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Sungkyunkwan University · KRAjou University · KR

Funding

National Research Foundation of Korea NRF-2018R1A2A1A05078102Technology development Program of MSS S3201794
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a highly prevalent gut inflammatory disorder. Complicated clinical outcomes prolong the use of conventional therapy and often lead to compromised immunity followed by adverse events and high relapse rates. Thus, a profound medical intervention is required. Previously, intranasal immunization of pneumococcal

Indexed as

caspase-14gut microbiomeimmune toleranceinflammatory bowel disease∆pep27regulatory T cells

Identifiers

PMID36144473
PMCPMC9502188
OpenAlexW4296742039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.