Evidence map›Paper›PMID 36144285›Full record

ArticleMetabolites2022

Association of Metabolic Signatures with Nonalcoholic Fatty Liver Disease in Pediatric Population.

Woori Chae, Kyung Jae Lee, Ki Young Huh, Jin Soo Moon, Jae Sung Ko, Joo-Youn Cho

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Woori ChaeDepartment of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul 03080, Korea.ORCID 0000-0001-7968-1504
Kyung Jae LeeDepartment of Pediatrics, Hallym University Sacred Heart Hospital, Anyang 14068, Korea.
Ki Young HuhDepartment of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul 03080, Korea.ORCID 0000-0002-1872-9954
Jin Soo MoonDepartment of Pediatrics, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0000-0001-9760-297X
Jae Sung KoDepartment of Pediatrics, Seoul National University College of Medicine, Seoul 03080, Korea.
Joo-Youn ChoDepartment of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul 03080, Korea.ORCID 0000-0001-9270-8273
Seoul National University · KRHallym University Sacred Heart Hospital · KRSeoul National University Hospital · KR

Funding

National Research Foundation of Korea NRF-2019R1F1A1057588
6 · The paper itself

Abstract

Several adult omics studies have been conducted to understand the pathophysiology of nonalcoholic fatty liver disease (NAFLD). However, the histological features of children are different from those of adults, and the onset and progression of pediatric NAFLD are not fully understood. In this study, we aimed to evaluate the metabolome profile and metabolic pathway changes associated with pediatric NAFLD to elucidate its pathophysiology and to develop machine learning-based NAFLD diagnostic models. We analyzed the metabolic profiles of healthy control, lean NAFLD, overweight control, and overweight NAFLD groups of children and adolescent participants (

Indexed as

hepatic steatosismachine learningnonalcoholic fatty liver diseasepediatric obesityplasma metabolomics

Identifiers

PMID36144285
PMCPMC9503976
OpenAlexW4296364277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.