Evidence map›Paper›PMID 36144234›Full record

ArticleMetabolites2022

Comprehensive Metabolic Profiling of Euphorbiasteroid in Rats by Integrating UPLC-Q/TOF-MS and NMR as Well as Microbial Biotransformation.

Sijia Xiao, Xike Xu, Xintong Wei, Jiayun Xin, Shanshan Li, Yanhui Lv, Wei Chen, Wenlin Yuan, Bin Xie, Xianpeng Zu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Natural Products Inhibition of Cytochrome P450 2B6 Activity and Methadone Metabolism.Drug metabolism and disposition: the biological fate of chemicals · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Sijia XiaoSchool of Pharmacy, Naval Medical University, Shanghai 200433, China.
Xike XuSchool of Pharmacy, Naval Medical University, Shanghai 200433, China.
Xintong WeiSchool of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Jiayun XinSchool of Pharmacy, Naval Medical University, Shanghai 200433, China.
Shanshan LiSchool of Pharmaceutical Sciences and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650500, China.
Yanhui LvSchool of Pharmacy, Naval Medical University, Shanghai 200433, China.
Wei ChenSchool of Pharmacy, Naval Medical University, Shanghai 200433, China.
Wenlin YuanSchool of Pharmacy, Naval Medical University, Shanghai 200433, China.ORCID 0000-0003-4759-8452
Bin XieSchool of Pharmacy, Naval Medical University, Shanghai 200433, China.
Xianpeng ZuSchool of Pharmacy, Naval Medical University, Shanghai 200433, China.ORCID 0000-0003-2682-0755
Yunheng ShenSchool of Pharmacy, Naval Medical University, Shanghai 200433, China.ORCID 0000-0002-8107-1593
Second Military Medical University · CNShandong University of Traditional Chinese Medicine · CNKunming Medical University · CN

Funding

National Major Project of China 2018ZX09731016-005National Natural Science Foundation of China 82173704, 31870327, 82004215, 82073981Sailing Program of Naval Medical University nothingShanghai Engineering Research Center for the Preparation of Bioactive Natural Products 16DZ2280200Shanghai Municipal Health Commission Project 20204Y0326the Key Research and Development Program of China 2017YFC1702002, 2019YFC1711006Three-year Action Plan for Shanghai TCM Development and Inheritance Program ZY(2021-2023)-0401
6 · The paper itself

Abstract

Euphorbiasteroid, a lathyrane-type diterpene from

Indexed as

Cunninghamella eleganseuphorbiasteroidmetabolic pathway in vivomicrobial biotransformationUPLC-Q/TOF-MS

Identifiers

PMID36144234
PMCPMC9504842
OpenAlexW4294839498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.