Evidence map›Paper›PMID 36144233›Full record

ArticleMetabolites2022

Maternal Serum and Placental Metabolomes in Association with Prenatal Phthalate Exposure and Neurodevelopmental Outcomes in the MARBLES Cohort.

Mariana Parenti, Rebecca J Schmidt, Sally Ozonoff, Hyeong-Moo Shin, Daniel J Tancredi, Paula Krakowiak, Irva Hertz-Picciotto, Cheryl K Walker, Carolyn M Slupsky

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mariana ParentiDepartment of Nutrition, University of California, Davis, CA 95616, USA.
Rebecca J SchmidtDepartment of Public Health Sciences, University of California, Davis, CA 95616, USA.ORCID 0000-0003-1582-2747
Sally OzonoffMedical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California, Davis, CA 95616, USA.
Hyeong-Moo ShinDepartment of Environmental Science, Baylor University, Waco, TX 76798, USA.ORCID 0000-0002-7001-2555
Daniel J TancrediDepartment of Pediatrics, School of Medicine, University of California, Davis, CA 95616, USA.ORCID 0000-0002-3884-7907
Paula KrakowiakDepartment of Public Health Sciences, University of California, Davis, CA 95616, USA.
Irva Hertz-PicciottoDepartment of Public Health Sciences, University of California, Davis, CA 95616, USA.ORCID 0000-0001-6952-2390
Cheryl K WalkerMedical Investigation of Neurodevelopmental Disorders (MIND) Institute, University of California, Davis, CA 95616, USA.
Carolyn M SlupskyDepartment of Nutrition, University of California, Davis, CA 95616, USA.ORCID 0000-0002-5100-1594
University of California, Davis · USBaylor University · US

Funding

Statistical Services and Methods Development ResourceU2CES026555 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI TEITELBAUM, SUSAN L · 2015 to 2025
$26.4M
UC Davis Environmental Health Sciences Core CenterP30ES023513 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Irva Hertz-Picciotto · 2015 to 2026
$26.0M
THE CHARGE STUDY: CHILDHOOD AUTISM RISKS FROM GENETICS AND THE ENVIRONMENT - ADMINISTRATIVE SUPPLEMENTR01ES015359 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HERTZ-PICCIOTTO, IRVA · 2007 to 2019
$13.8M
UC Davis Center for Children's Environmental Health (CCEH)P01ES011269 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI VAN DE WATER, JUDY A. · 2001 to 2018
$12.5M
Autism Risk, Prenatal Environmental Exposures, and Pathophysiologic MarkersR01ES020392 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HERTZ-PICCIOTTO, IRVA, OZONOFF, SALLY · 2011 to 2015
$9.0M
Rodent Behavior CoreU54HD079125 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ABBEDUTO, LEONARD J. · 2013 to 2019
$8.5M
ENVIRONMENTAL TOXICOLOGYT32ES007059 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI Laura S Van Winkle · 1985 to 2026
$7.9M
Environmental Influence on Infant Microbiome Development and ASD SymptomsR01ES028089 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HERTZ-PICCIOTTO, IRVA, MILLS, DAVID ANDREW · 2016 to 2020
$3.6M
BUILDS MARBLES: Biorepository Upkeep and Infrastructure for Longitudinal Data Sharing for MARBLESR24ES028533 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Brittany D. Chambers Butcher, Rebecca Jean Schmidt · 2017 to 2026
$2.3M
BUILDS MARBLES: Biorepository Upkeep and Infrastructure for Longitudinal Data Sharing for MARBLESU24ES028533 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHAMBERS BUTCHER, BRITTANY D., SCHMIDT, REBECCA JEAN · 2023 to 2025
$1.2M
Prenatal Exposure to Phthalates in a High-Risk ASD Pregnancy CohortR21ES025551 · NIEHS · UNIVERSITY OF TEXAS ARLINGTON · PI SHIN, HYEONG-MOO · 2015 to 2016
$431k
Metabolic and Microbiome Mechanisms Linking Gestational Phthalate Exposure with Child ASD RiskR21ES028129 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SLUPSKY, CAROLYN, WALKER, CHERYL KATHERINE · 2017 to 2018
$425k
NICHD NIH HHS U54 HD079125NIEHS NIH HHS P01 ES011269NIEHS NIH HHS P30 ES023513NIEHS NIH HHS R01 ES015359NIEHS NIH HHS R01 ES020392NIEHS NIH HHS R01 ES028089NIEHS NIH HHS R21 ES025551NIEHS NIH HHS R21 ES028129NIEHS NIH HHS R24 ES028533NIEHS NIH HHS T32 ES007059NIEHS NIH HHS U24 ES028533NIEHS NIH HHS U2C ES026555NIH HHS P01ES11269NIH HHS R01ES015359NIH HHS R01ES020392NIH HHS R21ES025551NIH HHS R21ES028129NIH HHS T32 ES007059NIH HHS U54HD079125
6 · The paper itself

Abstract

Prenatal exposure to phthalates, a family of endocrine-disrupting plasticizers, is associated with disruption of maternal metabolism and impaired neurodevelopment. We investigated associations between prenatal phthalate exposure and alterations of both the maternal third trimester serum metabolome and the placental metabolome at birth, and associations of these with child neurodevelopmental outcomes using data and samples from the Markers of Autism Risk in Babies Learning Early Signs (MARBLES) cohort. The third trimester serum (

Indexed as

autismNMRphthalatesplacentaprenatal exposureserum

Identifiers

PMID36144233
PMCPMC9500898
OpenAlexW4294838990

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.