ReviewMetabolites2022
The Human Skin Volatolome: A Systematic Review of Untargeted Mass Spectrometry Analysis.
Review in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05600608 (Augmentation of Volatile Biomarkers of Oesophageal and Gastric Adenocarcinoma From the Tumour Lipidome), which is not on this map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Augmentation of Volatile Biomarkers of Oesophageal and Gastric Adenocarcinoma From the Tumour Lipidome
Who cites it
19 citing papers in PubMed.
- Methodological assessment of PDMS passive sampling for skin VOC collection across body sites.bioRxiv : the preprint server for biology · 2026Article
- Sweat as a diagnostic biofluid: analytical advances and future directions.Journal of pharmaceutical analysis · 2026Review
- Viral infections alter the human salivary volatilome.mSphere · 2026Article
- Development of an Enzyme-Based Electrochemical Acetone Gas Sensor Printed on a Porous Polyimide Film.ACS omega · 2026Article
- Measurement of Dermal Ammonia Emission Using a Passive Flux Sampler and Its Association with Autonomic Nervous System Activity in Medical Workers: A Preliminary Study.Sensors (Basel, Switzerland) · 2026Article
- Local heating increases skin gas acetone content independent of systemic metabolism.Scientific reports · 2026Article
- Differentiating superficial fungal infection from eczema using a heated dynamic-headspace skin VOC sampler: a hypothesis.Frontiers in medicine · 2026Article
- Solid-phase microextraction of sweat components of patients positive for Sars-Cov-2 for identification of possible biomarkers.Scientific reports · 2025Article
- Volatile organic compounds (VOCs) detection for the identification of bacterial infections in clinical wound samples.Talanta · 2025Review
- Colorectal Cancer Detection Through Sweat Volatilome Using an Electronic Nose System and GC-MS Analysis.Cancers · 2025Article
- Detection of Volatile Organic Compounds as an emerging strategy for Parkinson's disease diagnosis and monitoring.NPJ Parkinson's disease · 2025Article
- A device for volatile organic compound (VOC) analysis from skin using heated dynamic headspace sampling.Journal of breath research · 2025Article
- A Comprehensive Skin Gas Analysis of Substances Related to Uraemia in Patients With End-Stage Kidney Disease: A Pilot Study.Nephrology (Carlton, Vic.) · 2025Article
- Volatile organic compound detection of Buruli ulcer disease: Headspace analysis of Mycobacterium ulcerans and used gauzes of Buruli-compatible ulcers.PLoS neglected tropical diseases · 2024Article
- Skin emitted volatiles analysis for noninvasive diagnosis: the current advances in sample preparation techniques for biomedical application.RSC advances · 2024Review
- Human skin gas profile of individuals with the people allergic to me phenomenon.Scientific reports · 2023Article
- A Review of Skin-Wearable Sensors for Non-Invasive Health Monitoring Applications.Sensors (Basel, Switzerland) · 2023Review
- Unraveling the potential of breath and sweat VOC capture devices for human disease detection: a systematic-like review of canine olfaction and GC-MS analysis.Frontiers in chemistry · 2023Review
- A Case of Acute Poisoning Due to Ortho-Dichlorobenzene Diagnosed Using Biological Volatile Gas Analysis.Acute medicine & surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The analysis of volatile organic compounds (VOCs) can provide important clinical information (entirely non-invasively); however, the exact extent to which VOCs from human skin can be signatures of health and disease is unknown. This systematic review summarises the published literature concerning the methodology, application, and volatile profiles of skin VOC studies. An online literature search was conducted in accordance with the preferred reporting items for systematic reviews and meta-analysis, to identify human skin VOC studies using untargeted mass spectrometry (MS) methods. The principal outcome was chemically verified VOCs detected from the skin. Each VOC was cross-referenced using the CAS number against the Human Metabolome and KEGG databases to evaluate biological origins. A total of 29 studies identified 822 skin VOCs from 935 participants. Skin VOCs were commonly sampled from the hand (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.