Juxtapapillary Choroidal Neovascularization in a Young Woman with Tubulointerstitial Nephritis and Uveitis (TINU) Syndrome with Onset in Pediatric Age.

Maria Pia Paroli, Daniele Cappiello, Davide Staccini, Anna Clara Tamburrelli, Marino Paroli, Ludovico Iannetti

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In one paragraph

Article in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.1field-weighted citation impact, top 52% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maria Pia ParoliEye Clinic, Department of Sense Organs, Sapienza University of Rome, Policlinico Umberto I Hospital, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0002-4395-4774

Daniele CappielloEye Clinic, Department of Sense Organs, Sapienza University of Rome, Policlinico Umberto I Hospital, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0002-8537-353X

Davide StacciniEye Clinic, Department of Sense Organs, Sapienza University of Rome, Policlinico Umberto I Hospital, Viale del Policlinico 155, 00161 Rome, Italy.

Anna Clara TamburrelliEye Clinic, Department of Sense Organs, Sapienza University of Rome, Policlinico Umberto I Hospital, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0003-4281-1103

Marino ParoliDepartment of Clinical, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, ICOT Hospital, 04100 Latina, Italy.ORCID 0000-0001-7919-9128

Ludovico IannettiEye Clinic, Department of Sense Organs, Sapienza University of Rome, Policlinico Umberto I Hospital, Viale del Policlinico 155, 00161 Rome, Italy.ORCID 0000-0003-1790-3532

Policlinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the unusual case of a young woman with tubulointerstitial nephritis and uveitis (TINU) with bilateral diffuse uveitis and optic nerve inflammatory involvement since she was a child in the 1990s. Imaging diagnostic tools such as fluorescein angiography, indocyanine green angiography, optical coherence tomography (OCT), and OCT angiography revealed inactive juxtapapillary choroidal neovascularization (CNV) after 25 years of follow-up. After treatment, uveitis went into remission with BCVA 20/20 in both eyes and CNV lesions became inactive. Although anterior uveitis is more frequently reported in TINU, posterior uveitis with inflammatory involvement of the optic nerve should be accurately investigated to rule out juxtapapillary CNV, both at the time of active uveitis and during follow-up, since TINU may be complicated by CNV even at the later stages of the inflammatory process.

Indexed as

Choroidal NeovascularizationNephritis, InterstitialUveitisChildFemaleHumansIndocyanine GreenIndocyanine Greendiffuse uveitisjuxtapapillary choroidal neovascularizationoptic disk edemaTINU syndrome

Identifiers

PMID36143936

DOI10.3390/medicina58091260

PMCPMC9503526

OpenAlexW4296007416

What OpenQuestion holds

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.