ReviewLife (Basel, Switzerland)2022
Origins of Life Research: The Conundrum between Laboratory and Field Simulations of Messy Environments.
Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Low-Molecular-Weight Polyols as Key Factors in Sulfur- and Borate-Mediated Protomembrane Formation Before the RNA World.Membranes · 2026Review
- Borate-Bridged Protolipids: A Prebiotic Route to Abiotic Membranes.Life (Basel, Switzerland) · 2026Article
- Chemical Routes to Primitive Membranes: Prebiotic Lipid Formation at the Origin of Life.Life (Basel, Switzerland) · 2026Review
- G-quadruplexes self-assembled from nucleotide monomers as stable prepolymer scaffolds in aqueous environments.Scientific reports · 2026Article
- Who Decides What Is Prebiotically Plausible? The Risks of Premature Constraints in Origin-of-Life Research.Life (Basel, Switzerland) · 2025Article
- Reciprocating thermochemical mediator of pre-biotic polymer decomposition on mineral surfaces.Journal of the Royal Society, Interface · 2025Article
- Template-based copying in chemically fuelled dynamic combinatorial libraries.Nature chemistry · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most experimental results that guide research related to the origin of life are from laboratory simulations of the early Earth conditions. In the laboratory, emphasis is placed on the purity of reagents and carefully controlled conditions, so there is a natural tendency to reject impurities and lack of control. However, life did not originate in laboratory conditions; therefore, we should take into consideration multiple factors that are likely to have contributed to the environmental complexity of the early Earth. This essay describes eight physical and biophysical factors that spontaneously resolve aqueous dispersions of ionic and organic solutes mixed with mineral particles and thereby promote specific chemical reactions required for life to begin.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.