Evidence map›Paper›PMID 36143445›Full record

ArticleLife (Basel, Switzerland)2022

Discovery of Potential SARS-CoV-2 Papain-like Protease Natural Inhibitors Employing a Multi-Phase In Silico Approach.

Eslam B Elkaeed, Ahmed M Metwaly, Mohamed S Alesawy, Abdulrahman M Saleh, Aisha A Alsfouk, Ibrahim H Eissa

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Chemistry and Biological Activity of 11Molecules (Basel, Switzerland) · 2026
    Review
  3. Article
  4. IntegratedCurrent medicinal chemistry · 2025
    Article
  5. Arctigenin fromInternational journal of molecular sciences · 2024
    Article
  6. Article
  7. The Essential Oil ofPlants (Basel, Switzerland) · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eslam B ElkaeedDepartment of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh 13713, Saudi Arabia.ORCID 0000-0002-2546-8035
Ahmed M MetwalyPharmacognosy and Medicinal Plants Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0001-8566-1980
Mohamed S AlesawyPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0001-9202-1754
Abdulrahman M SalehPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0002-5153-7399
Aisha A AlsfoukDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.ORCID 0000-0003-4497-5013
Ibrahim H EissaPharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt.ORCID 0000-0002-6955-2263

Funding

Princess Nourah bint Abdulrahman University PNURSP2022R116
6 · The paper itself

Abstract

As an extension of our research against COVID-19, a multiphase

Indexed as

ADMETDFTmolecular dockingnatural productspapain-like proteaseSARS-CoV-2structural similarity

Identifiers

PMID36143445
PMCPMC9505301

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.