Evidence map›Paper›PMID 36143439›Full record

ReviewLife (Basel, Switzerland)2022

Fundamentals and Applications of the Receiver Operating Characteristic Curve Analysis in the Research of Endothelial Dysfunction in Chronic Kidney Disease.

Stefanos Roumeliotis, Samar Abd ElHafeez, Graziella D'Arrigo, Maria Fusaro, Daniela Leonardis, Sabrina Mezzatesta, Giovanni Tripepi

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Stefanos RoumeliotisDivision of Nephrology and Hypertension, 1st Department of Internal Medicine, AHEPA Hospital, School of Medicine, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.ORCID 0000-0002-9423-649X
Samar Abd ElHafeezEpidemiology Department, High Institute of Public Health, Alexandria University, Alexandria 21561, Egypt.ORCID 0000-0002-3250-2780
Graziella D'ArrigoClinical Epidemiology of Renal Diseases and Hypertension Unit, Institute of Clinical Physiology, 89124 Reggio Calabria, Italy.
Maria FusaroNational Research Council (CNR), Institute of Clinical Physiology (IFC), 56124 Pisa, Italy.ORCID 0000-0001-9478-4851
Daniela LeonardisClinical Epidemiology of Renal Diseases and Hypertension Unit, Institute of Clinical Physiology, 89124 Reggio Calabria, Italy.ORCID 0000-0002-0575-1191
Sabrina MezzatestaClinical Epidemiology of Renal Diseases and Hypertension Unit, Institute of Clinical Physiology, 89124 Reggio Calabria, Italy.
Giovanni TripepiClinical Epidemiology of Renal Diseases and Hypertension Unit, Institute of Clinical Physiology, 89124 Reggio Calabria, Italy.
Istituto di Fisiologia Clinica · ITAlexandria University · EGAristotle University of Thessaloniki · GRUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial dysfunction (ED) starts early in chronic kidney disease (CKD) and is the hallmark of atherosclerosis in these patients. During recent years, numerous markers have emerged, aiming to predict the onset of ED in CKD patients. Therefore, there is a need to evaluate and assess the discriminatory ability (or diagnostic accuracy) of such a marker (i.e., the ability to correctly classify individuals as having a given disease or not) and identify the optimal cut-off value. A receiver operating characteristic (ROC) curve analysis has been used in the majority of the research papers evaluating the predictive ability of a marker of ED. It is a graphical plot combining pairs of sensitivity (true positive rate) on the

Indexed as

classificationdiagnostic testdiscriminatory powerendothelial dysfunctionreceiver operating characteristic curvessensitivityspecificitystatistical test

Identifiers

PMID36143439
PMCPMC9505049
OpenAlexW4295539377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.