Evidence map›Paper›PMID 36143426›Full record

ArticleLife (Basel, Switzerland)2022

Urinary Collectrin (TMEM27) as Novel Marker for Acute Kidney Injury.

Sahra Pajenda, Ludwig Wagner, Daniela Gerges, Harald Herkner, Tamar Tevdoradze, Karl Mechtler, Alice Schmidt, Wolfgang Winnicki

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Turner Syndrome and the Thyroid Function-A Systematic and Critical Review.International journal of molecular sciences · 2024
    Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sahra PajendaDepartment of Internal Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, 1090 Vienna, Austria.
Ludwig WagnerDepartment of Internal Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, 1090 Vienna, Austria.
Daniela GergesDepartment of Internal Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, 1090 Vienna, Austria.
Harald HerknerDepartment of Emergency Medicine, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-1329-6149
Tamar TevdoradzeDepartment of Renal Replacement Therapy, Nephrology and Transplantation, Tbilisi State Medical University and Ingorokva High Medical Technology University Clinic, Tbilisi 0144, Georgia.ORCID 0000-0002-5703-6499
Karl MechtlerProtChem Facility, IMP-IMBA, Research Institute of Molecular Pathology, 1030 Vienna, Austria.ORCID 0000-0002-3392-9946
Alice SchmidtDepartment of Internal Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, 1090 Vienna, Austria.
Wolfgang WinnickiDepartment of Internal Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-0511-6120
Medical University of Vienna · ATResearch Institute of Molecular Pathology · ATTbilisi State Medical University · GE

Funding

Medical Scientific Fund of the Mayor of the City of Vienna 22100
6 · The paper itself

Abstract

Acute kidney injury (AKI) is a leading complication in hospitalized patients of different disciplines due to various aetiologies and is associated with the risk of chronic kidney disease, the need for dialysis and death. Since nephrons are not supplied with pain signals, kidney injury is mostly diagnosed by serum creatinine with a time delay. Recent work has shown that certain urinary biomarkers are available for early detection of AKI. In total, 155 subjects, including 102 patients with AKI at various stages and 53 subjects without AKI, were enrolled, and their course and laboratory data were recorded. Urinary collectrin (TMEM27) was measured by a commercially available ELISA assay. Changes in serum creatinine were used to determine AKI stage. Patients with AKI presented with significantly lower levels of urinary collectrin compared to patients without AKI (1597 ± 1827 pg/mL vs. 2855 ± 2073;

Indexed as

acute kidney injurybiomarkercollectrin

Identifiers

PMID36143426
PMCPMC9503639
OpenAlexW4294845580

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.