Evidence map›Paper›PMID 36143338›Full record

ArticleLife (Basel, Switzerland)2022

Exome-Wide Association Study Reveals Host Genetic Variants Likely Associated with the Severity of COVID-19 in Patients of European Ancestry.

Priyanka Upadhyai, Pooja U Shenoy, Bhavya Banjan, Mohammed F Albeshr, Shahid Mahboob, Irfan Manzoor, Ranajit Das

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. The peptidoglycan ofScience translational medicine · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. COVID-19 Prevention and Treatment.Life (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Priyanka UpadhyaiDepartment of Medical Genetics, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal 576104, India.ORCID 0000-0002-4319-7283
Pooja U ShenoyYenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India.
Bhavya BanjanManipal School of Life Sciences, Manipal Academy of Higher Education, Manipal 576104, India.ORCID 0000-0002-0159-3034
Mohammed F AlbeshrDepartment of Zoology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Shahid MahboobDepartment of Zoology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-4969-5387
Irfan ManzoorDepartment of Biology, The College of Arts and Sciences, Indiana University, Bloomington, IN 47405, USA.
Ranajit DasYenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore 575018, India.
King Saud University · SAManipal Academy of Higher Education · INYenepoya University · INIndiana University Bloomington · US

Funding

The APC was funded by Researchers Supporting Project, King Saud University, Riyadh, Saudi Arabia. RSP2022R436
6 · The paper itself

Abstract

Host genetic variability plays a pivotal role in modulating COVID-19 clinical outcomes. Despite the functional relevance of protein-coding regions, rare variants located here are less likely to completely explain the considerable numbers of acutely affected COVID-19 patients worldwide. Using an exome-wide association approach, with individuals of European descent, we sought to identify common coding variants linked with variation in COVID-19 severity. Herein,

Indexed as

common genetic variantsCOVID-19 host geneticsexome-wide association study for COVID-19 patientsgenetic variation in COVID-19 patients

Identifiers

PMID36143338
PMCPMC9504138
OpenAlexW4293219172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.