Evidence map›Paper›PMID 36143322›Full record

ArticleJournal of personalized medicine2022

Adequacy of Disease Control by Supraomohyoid Neck Dissection in cT1/T2 Tongue Cancer.

Andrea Iandelli, Filippo Marchi, An-Chieh Chen, Chi-Kuan Young, Chun-Ta Liao, Chung-Kan Tsao, Chung-Jan Kang, Hung-Ming Wang, Tung-Chieh Joseph Chang, Shiang-Fu Huang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Andrea IandelliDepartment of Otorhinolaryngology and Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou Branch, Yaoyuan 33302, Taiwan.ORCID 0000-0003-1187-3045
Filippo MarchiUnit of Otorhinolaryngology-Head and Neck Surgery, IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.ORCID 0000-0002-7997-964X
An-Chieh ChenDepartment of Otorhinolaryngology and Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou Branch, Yaoyuan 33302, Taiwan.
Chi-Kuan YoungDepartment of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial, Keelung Branch, Keelung 20401, Taiwan.
Chun-Ta LiaoDepartment of Otorhinolaryngology and Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou Branch, Yaoyuan 33302, Taiwan.
Chung-Kan TsaoDepartment of Plastic Surgery, Chang Gung Memorial, Linkou Branch, Taoyuan 333, Taiwan.
Chung-Jan KangDepartment of Otorhinolaryngology and Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou Branch, Yaoyuan 33302, Taiwan.ORCID 0000-0002-5333-9396
Hung-Ming WangSchool of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Tung-Chieh Joseph ChangSchool of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Shiang-Fu HuangDepartment of Otorhinolaryngology and Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou Branch, Yaoyuan 33302, Taiwan.ORCID 0000-0003-3582-9938
Chang Gung University · TWChang Gung Memorial Hospital · TW

Funding

Linkou Chang Gung Memorial Hospital CMRPG3L0861, CMRPG3J0593, CMRPG3M1101 and CMRPB53Ministry of Science and Technology, Taiwan MOST 110-2314-B-182 -045 -MY3
6 · The paper itself

Abstract

backgroundPatients affected by oral tongue squamous cell carcinoma (OTSCC) underwent a supraomohyoid neck dissection (SOHND) or modified radical neck dissection (mRND) according to the clinical nodal status (cN0 vs. cN+). We investigate whether the type of neck dissection affects survival with the presence of extranodal extension (ENE) and multiple nodal metastases (MNM).

methodsWe conducted a retrospective study enrolling surgically treated patients affected by cT1/T2 OTSCC and MNM or ENE. The outcomes assessed were: overall survival (OS), disease-free survival (DFS), and neck-control- and metastases-free survival (NC-MFS). Survival curves were plotted by the Kaplan-Meier method and the log-rank test. Furthermore, we conducted a multivariable analysis with the Cox regression model.

resultsWe included a total of 565 patients (36% cT1, 64% cT2). Of these, 501 patients underwent a SOHND, and 64 underwent an mRND. A total of 184 patients presented rpN+, with 28.7% of these in the SOHND group and 62.5% of these in the mRND group. We identified no significant differences in OS, DFS, and NC-MFS in the whole pN+ cohort, in the MNM, and the ENE subgroups. In the multivariable analysis, the type of ND did not affect OS and DFS.

conclusionsTreating cT1-2 N0/+ tongue cancer with SOHND is oncologically safe. ENE and MNM patients do not benefit from an mRND.

Indexed as

head and neck cancerneck dissectionoral cancerskip metastasessupraomohyoid neck dissectiontongue cancers

Identifiers

PMID36143322
PMCPMC9505271
OpenAlexW4296343552

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.