Evidence map›Paper›PMID 36143312›Full record

ReviewJournal of personalized medicine2022

Clinical Markers of Need for Surgery in Orbital Complication of Acute Rhinosinusitis in Children: Overview and Systematic Review.

Elena Cantone, Eva Piro, Eugenio De Corso, Claudio Di Nola, Stefano Settimi, Giusi Grimaldi, Gaetano Motta

Abstract readReview
In one paragraph

Review in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Outcomes of inflammatory markers in the diagnosis of complicated rhinosinusitis in children.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  2. Review
  3. Prognostic Factors of Pediatric Acute Ethmoidal Rhinosinusitis With Orbital Subperiosteal Abscess: A Retrospective Cohort Study.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elena CantoneDepartment of Neuroscience, Reproductive and Odontostomatological Sciences-ENT Section, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0002-7389-2033
Eva PiroDepartment of Neuroscience, Reproductive and Odontostomatological Sciences-ENT Section, University of Naples "Federico II", 80131 Naples, Italy.
Eugenio De CorsoFondazione Policlinico Universitario A. Gemelli IRCCS, Head and Neck Surgery-Otorhinolaryngology, 00168 Rome, Italy.ORCID 0000-0001-5761-7018
Claudio Di NolaDepartment of Neuroscience, Reproductive and Odontostomatological Sciences-ENT Section, University of Naples "Federico II", 80131 Naples, Italy.
Stefano SettimiFondazione Policlinico Universitario A. Gemelli IRCCS, Head and Neck Surgery-Otorhinolaryngology, 00168 Rome, Italy.ORCID 0000-0003-0104-1501
Giusi GrimaldiDepartment of Neuroscience, Reproductive and Odontostomatological Sciences-ENT Section, University of Naples "Federico II", 80131 Naples, Italy.
Gaetano MottaOtorhinolaryngology, Head and Neck Surgery Unit, Department of Mental and Physical Health and Preventive Medicine, Università degli Studi della Campania Luigi Vanvitelli, 80131 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough they can occur at all ages, orbital (OC) and periorbital cellulitis (POC) prevail in the pediatric population. Acute rhinosinusitis (ARS) is the most frequent predisposing factor of OC. Recent literature has suggested a medical management approach for OC and POC, with surgery reserved only for more severe cases. However, there is still a lack of consensus on the clinical markers of a need for surgery. The aim of this systematic review was to identify clinical markers of a need for surgery in children with OC. Our systematic review, in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) process, yielded 1289 articles finally screened. This resulted in 31 full texts that were included in a qualitative analysis. The results of this review suggest that in children aged over 9 years, large subperiosteal orbital abscesses (SPOAs), impaired vision, ophthalmoplegia, proptosis, elevated C-reactive protein (CRP) and absolute neutrophil counts (ANC), hemodynamic compromise, no clinical improvement after 48/72 h of antibiotic therapy, and a Chandler III score or higher are clinical markers of the need for surgery. However, most of the studies are observational and retrospective, and further studies are needed to identify reliable and repeatable clinical markers of the need for surgery.

Indexed as

acute rhinosinusitischildrenFESSophthalmoplegiaorbital cellulitisorbital surgeryperiorbital cellulitisproptosissubperiosteal abscess

Identifiers

PMID36143312
PMCPMC9504785

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.