Evidence map›Paper›PMID 36143309›Full record

ArticleJournal of personalized medicine2022

Possible Use of Minocycline in Adjunction to Intranasal Esketamine for the Management of Difficult to Treat Depression following Extensive Pharmacogenomic Testing: Two Case Reports.

Matteo Marcatili, Riccardo Borgonovo, Noemi Cimminiello, Ranieri Domenico Cornaggia, Giulia Casati, Cristian Pellicioli, Laura Maggioni, Federico Motta, Chiara Redaelli, Luisa Ledda and 18 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 5 institutions in 2 countries.

Matteo MarcatiliPsychiatric Department, San Gerardo Hospital, ASST Monza, 20900 Monza, Italy.ORCID 0000-0002-1436-1961
Riccardo BorgonovoDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.
Noemi CimminielloDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.
Ranieri Domenico CornaggiaDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.
Giulia CasatiDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.
Cristian PellicioliDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.
Laura MaggioniDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.
Federico MottaDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.ORCID 0000-0003-1249-4397
Chiara RedaelliDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.
Luisa LeddaDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.
Federico Emanuele PozziDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.
Michaela KrivosovaDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.
Jessica PaganoNational Research Council Neuroscience Institute, 20100 Milan, Italy.
Roberto NavaPsychiatric Department, San Gerardo Hospital, ASST Monza, 20900 Monza, Italy.
Fabrizia ColmegnaPsychiatric Department, San Gerardo Hospital, ASST Monza, 20900 Monza, Italy.ORCID 0000-0002-4984-9908
Antonios DakanalisDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.ORCID 0000-0002-2328-3862
Alice CaldiroliPsychiatric Department, San Gerardo Hospital, ASST Monza, 20900 Monza, Italy.ORCID 0000-0002-8493-0779
Enrico CapuzziPsychiatric Department, San Gerardo Hospital, ASST Monza, 20900 Monza, Italy.
Beatrice BenattiPsychiatry Unit, Department of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, 20100 Milan, Italy.
Bernardo Dell'OssoPsychiatry Unit, Department of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, 20100 Milan, Italy.
Francesca BertolaCytogenetics and Medical Genetics Unit, Centre for Disorders of Iron Metabolism, San Gerardo Hospital, ASST Monza, 20900 Monza, Italy.
Nicoletta VillaCytogenetics and Medical Genetics Unit, Centre for Disorders of Iron Metabolism, San Gerardo Hospital, ASST Monza, 20900 Monza, Italy.
Alberto PipernoDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.
Silvia IppolitoClinical Chemistry Laboratory, San Gerardo Hospital, ASST Monza, 20900 Monza, Italy.
Ildebrando AppollonioDepartment of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.ORCID 0000-0003-4717-6479
Carlo SalaNational Research Council Neuroscience Institute, 20100 Milan, Italy.ORCID 0000-0003-0662-9523
Luciano ContiLaboratory of Stem Cell Biology, Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38122 Trento, Italy.ORCID 0000-0002-2050-9846
Massimo ClericiPsychiatric Department, San Gerardo Hospital, ASST Monza, 20900 Monza, Italy.
Azienda Ospedaliera San Gerardo · ITUniversity of Milano-Bicocca · ITNeuroscience Institute · ITUniversity of Milan · ITUniversity of Trento · IT

Funding

Fondazione Cariplo 2019-3396
6 · The paper itself

Abstract

The advent of intra-nasal esketamine (ESK), one of the first so called

Indexed as

difficult to treat depression (DTD)esketamineketaminemajor depressive disorder (MDD)minocyclinepharmacogeneticstreatment resistant depression (TRD)

Identifiers

PMID36143309
PMCPMC9503866
OpenAlexW4296356673

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.