Evidence map›Paper›PMID 36143285›Full record

ArticleJournal of personalized medicine2022

Open Innovation as the Catalyst in the Personalized Medicine to Personalized Digital Medicine Transition.

Alfredo Cesario, Marika D'Oria, Irene Simone, Stefano Patarnello, Vincenzo Valentini, Giovanni Scambia

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alfredo CesarioScientific Directorate, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00182 Rome, Italy.ORCID 0000-0003-4687-0709
Marika D'OriaScientific Directorate, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00182 Rome, Italy.ORCID 0000-0003-4253-8223
Irene SimoneScientific Directorate, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00182 Rome, Italy.
Stefano PatarnelloGemelli Digital Medicine & Health, 00182 Rome, Italy.
Vincenzo ValentiniGemelli Digital Medicine & Health, 00182 Rome, Italy.
Giovanni ScambiaScientific Directorate, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00182 Rome, Italy.
Agostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Personalized medicine (PM) bridges several disciplines for understanding and addressing prevalent, complex, or rare situations in human health (e.g., complex phenotyping, risk stratification, etc.); therefore, digital and technological solutions have been integrated in the field to boost innovation and new knowledge generation. The open innovation (OI) paradigm proposes a method by which to respectfully manage disruptive change in biomedical organizations, as experienced by many organizations during digital transformation and the COVID-19 pandemic. In this article, we focus on how this paradigm has catalyzed the transition from PM to personalized digital medicine in a large-volume research hospital. Methods, challenges, and results are discussed. This case study is an endeavor to confirm that OI strategies could help manage urgent needs from the healthcare environment, while achieving sustainability-oriented, accountable innovation.

Indexed as

digital medicineinterdisciplinarityknowledgeopen innovationpersonalized medicine

Identifiers

PMID36143285
PMCPMC9505138
OpenAlexW4295780307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.