Evidence map›Paper›PMID 36143266›Full record

ArticleJournal of personalized medicine2022

Impella RP for Patients with Acute Right Ventricular Failure and Cardiogenic Shock: A Subanalysis from the IMP-IT Registry.

Giulia Botti, Mario Gramegna, Francesco Burzotta, Giulia Masiero, Carlo Briguori, Carlo Trani, Massimo Napodano, Anna Mara Scandroglio, Matteo Montorfano, Giuseppe Tarantini and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Recent Developments in Ventricular Assist Device Therapy.Reviews in cardiovascular medicine · 2025
    Review
  10. Venous Thromboembolism: Current Insights and Future Directions.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024
    Review
  11. Cardioprotection in cardiovascular surgery.Basic research in cardiology · 2024
    Review
  12. Observational
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Giulia BottiVita Salute San Raffaele University, 20132 Milan, Italy.ORCID 0000-0002-7239-8850
Mario GramegnaCardiac and Cardiac Surgery Intensive Care Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.ORCID 0000-0002-9709-6082
Francesco BurzottaDepartment of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-6569-9401
Giulia MasieroDepartment of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua Medical School, 35128 Padua, Italy.
Carlo BriguoriLaboratory of Interventional Cardiology and Department of Cardiology, Mediterranea Cardiocentro, 80122 Naples, Italy.
Carlo TraniDepartment of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Massimo NapodanoDepartment of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua Medical School, 35128 Padua, Italy.
Anna Mara ScandroglioCardiac and Cardiac Surgery Intensive Care Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Matteo MontorfanoInterventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Giuseppe TarantiniDepartment of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua Medical School, 35128 Padua, Italy.
Alaide ChieffoInterventional Cardiology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
IMP IT Investigators
Vita-Salute San Raffaele University · ITUniversity of Padua · ITUniversità Cattolica del Sacro Cuore · ITClinica Mediterranea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of percutaneous right ventricular assist devices (pRVADs) to support patients with right ventricular (RV)-predominant cardiogenic shock (CS) refractory to optimal medical therapy is increasing progressively, and the Impella RP is the first FDA-approved pRVAD in such a clinical scenario. The aim of the present study is to report the outcomes of patients treated with Impella RP in the IMP-IT (IMPella Mechanical Circulatory Support Device in Italy) registry, a multicenter registry that evaluated the trends in use and clinical outcomes of the Impella in the setting of CS and high-risk percutaneous coronary intervention in Italy. A total of 15 patients who received Impella RP were enrolled. In 40% of the patients, the main cause was ST-segment elevation myocardial infarction. A total of 40% of patients required biventricular support with a left Impella. Device-related complications were reported in 46.7% of patients. Overall, the in-hospital mortality was 46.7%, whereas the one-year mortality was 53.3%. The composite rate of all-cause death, heart failure (HF) hospitalization, left ventricular assist device (LVAD) and heart transplant at one year was 60%. The Impella RP has favorable survival outcomes in RV-predominant cardiogenic shock. However, the device-related complications are frequent and should be carefully weighed when considering escalation to Impella RP.

Indexed as

cardiogenic shockImpella RPpercutaneous right ventricular assist deviceright ventricular failure

Identifiers

PMID36143266
PMCPMC9506315
OpenAlexW4295540017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.