Evidence map›Paper›PMID 36143257›Full record

ArticleJournal of personalized medicine2022

Moderate COVID-19: Clinical Trajectories and Predictors of Progression and Outcomes.

Apostolos G Pappas, Andreas Panagopoulos, Artemis Rodopoulou, Michaella Alexandrou, Anna-Louiza Chaliasou, Konstantinos Skianis, Eleftheria Kranidioti, Eleftheria Chaini, Ilias Papanikolaou, Ioannis Kalomenidis

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Investigating a middle‑step COVID‑19 unit in Greece.Experimental and therapeutic medicine · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Apostolos G Pappas1st Department of Critical Care & Pulmonary Service, School of Medicine, Evangelismos General Hospital, National and Kapodistrian University of Athens, 10676 Athens, Greece.
Andreas PanagopoulosCOVID-19 Unit, "Evangelismos" General Hospital, 10676 Athens, Greece.ORCID 0000-0003-0246-5082
Artemis RodopoulouCOVID-19 Unit, "Evangelismos" General Hospital, 10676 Athens, Greece.
Michaella Alexandrou1st Department of Critical Care & Pulmonary Service, School of Medicine, Evangelismos General Hospital, National and Kapodistrian University of Athens, 10676 Athens, Greece.
Anna-Louiza ChaliasouCOVID-19 Unit, "Evangelismos" General Hospital, 10676 Athens, Greece.
Konstantinos SkianisData Science & Mining Team, École Polytechnique, 91120 Paris, France.
Eleftheria KranidiotiCOVID-19 Unit, "Evangelismos" General Hospital, 10676 Athens, Greece.
Eleftheria ChainiPulmonary Department, Corfu General Hospital, 49100 Corfu, Greece.
Ilias PapanikolaouPulmonary Department, Corfu General Hospital, 49100 Corfu, Greece.ORCID 0000-0003-1391-2925
Ioannis Kalomenidis1st Department of Critical Care & Pulmonary Service, School of Medicine, Evangelismos General Hospital, National and Kapodistrian University of Athens, 10676 Athens, Greece.
Evangelismos Hospital · GRNational and Kapodistrian University of Athens · GRCorfu General Clinic · GRÉcole Polytechnique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with COVID-19 commonly present at healthcare facilities with moderate disease, i.e., pneumonia without a need for oxygen therapy.

aimTo identify clinical/laboratory characteristics of patients with moderate COVID-19, which could predict disease progression.

methods384 adult patients presented with moderate COVID-19 and admitted to two hospitals were retrospectively evaluated. In a multivariate analysis gender, age, BMI, Charlson Comorbidity Index (CCI) and National Early Weaning Score 2 were treated as co-variates. The development of hypoxemic respiratory failure, intubation rate and risk of death were considered as dependent variables. Estimated values are presented as odds-ratio (OR) with 95% confidence interval (CI).

resultsMost of the patients were male (63.28%) with a mean (standard deviation) age of 59 (16.04) years. Median (interquartile range) CCI was 2 (1-4). A total of 58.85% of the patients developed respiratory failure; 6.51% were intubated, and 8.85% died. The extent of pneumonia in chest X-ray (involvement of all four quartiles) [OR 3.96 (1.18-13.27),

conclusionOlder age, the extent of pneumonia, tachypnea, lower SatO

Indexed as

COVID-19moderate diseaserisk factorsSARS-CoV-2

Identifiers

PMID36143257
PMCPMC9505620
OpenAlexW4296117339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.