Evidence map›Paper›PMID 36143170›Full record

ArticleJournal of personalized medicine2022

Statistical Validation of Risk Alleles in Genetic Addiction Risk Severity (GARS) Test: Early Identification of Risk for Alcohol Use Disorder (AUD) in 74,566 Case-Control Subjects.

Kenneth Blum, David Han, Ashim Gupta, David Baron, Eric R Braverman, Catherine A Dennen, Shan Kazmi, Luis Llanos-Gomez, Rajendra D Badgaiyan, Igor Elman and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  18. Evidence for theClinical and experimental psychology · 2023
    Article
  19. How to Combat the Global Opioid Crisis.CPQ neurology and psychology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 3 countries.

Kenneth BlumGraduate College, Western University Health Sciences, Pomona, CA 91766, USA.ORCID 0000-0001-6727-803X
David HanDepartment of Management Science and Statistics, University of Texas at San Antonio, San Antonio, TX 78249, USA.
Ashim GuptaFuture Biologics, Lawrenceville, GA 30043, USA.ORCID 0000-0003-1224-2755
David BaronGraduate College, Western University Health Sciences, Pomona, CA 91766, USA.
Eric R BravermanThe Kenneth Blum Institute on Behavior & Neurogenetics, LLC., Austin, TX 78701, USA.
Catherine A DennenDepartment of Family Medicine, Jefferson Health Northeast, Philadelphia, PA 19114, USA.
Shan KazmiGraduate College, Western University Health Sciences, Pomona, CA 91766, USA.
Luis Llanos-GomezThe Kenneth Blum Institute on Behavior & Neurogenetics, LLC., Austin, TX 78701, USA.
Rajendra D BadgaiyanDepartment of Psychiatry, South Texas Veteran Health Care System, Audie L. Murphy Memorial VA Hospital, Long School of Medicine, University of Texas Medical Center, San Antonio, TX 78229, USA.ORCID 0000-0001-5586-5114
Igor ElmanCenter for Pain and the Brain (P.A.I.N Group), Department of Anesthesiology, Critical Care & Pain Medicine, Boston Children's Hospital, Boston, MA 02115, USA.
Panayotis K ThanosBehavioral Neuropharmacology and Neuroimaging Laboratory, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, Clinical Research Institute on Addictions, University at Buffalo, Buffalo, NY 14203, USA.
Bill W DownsDivision of Precision Nutrition, Victory Nutrition International, LLC., Lederoch, PA 19438, USA.ORCID 0000-0003-2096-8265
Debasis BagchiDivision of Precision Nutrition, Victory Nutrition International, LLC., Lederoch, PA 19438, USA.
Marjorie C Gondre-LewisDepartment of Psychiatry and Behavioral Sciences, Howard University College of Medicine, Washington, DC 20059, USA.
Mark S GoldDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA.
Abdalla BowirratDepartment of Molecular Biology, Adelson School of Medicine, Ariel University, Ariel 40700, Israel.ORCID 0000-0001-8185-0688
Western University of Health Sciences · USAriel University · ILCambridge Health Alliance · USClinical Research Institute · USEötvös Loránd University · HUHoward University · USTexas Medical Center · USTexas Southern University · USThe University of Texas at San Antonio · USThomas Jefferson University Hospital · USWashington University in St. Louis · US

Funding

Sleep Disorders in Adults with Sickle Cell Disease: Frequency, Associations with Cardiovascular and Pain Indicators, and Responses to TreatmentU54MD007597 · NIMHD · HOWARD UNIVERSITY · PI BYRON D. FORD · 2019 to 2026
$37.7M
SWG 2: Cure Research Scientific Working GroupP30AI117970 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Alan Edward Greenberg · 2015 to 2026
$29.6M
Excessive Alcohol Drinking Associated with GABA Alpha 2-Regulated TLR4 ExpressionR01AA021262 · NIAAA · HOWARD UNIVERSITY · PI AURELIAN, LAURE, GONDRE-LEWIS, MARJORIE C · 2013 to 2017
$2.3M
A Systematic Medical Approach to Reward Transformation (SMART) for Brain Health in Opioid Use DisorderR41MD012318 · NIMHD · VERSA INTEGRATED SOLUTIONS, INC. · PI BLUM, KENNETH, GONDRE-LEWIS, MARJORIE C · 2017 to 2017
$221k
Dopamine neurotransmission in Gulf War Veteran's IllnessI01CX002099 · VA · SOUTH TEXAS VETERANS HEALTH CARE SYSTEM · PI BADGAIYAN, RAJENDRA D · 2021 to 2021
–
CSRD VA I01 CX002099K.B. and M.C.G. are recipients of R41 MD012318/MD/NIMHD NIH HHS/United States. M.C.G. is recipient of following grants: P30 AI117970/AI/NIAID NIH HHS/United States; R01 AA021262/AA/NIAAA NIH HHS/United States; U54 MD007597/MD/NIMHD NIH HHS/United States; NANIAAA NIH HHS R01 AA021262NIAID NIH HHS P30 AI117970NIMHD NIH HHS R41 MD012318NIMHD NIH HHS U54 MD007597
6 · The paper itself

Abstract

Since 1990, when our laboratory published the association of the DRD2 Taq A1 allele and severe alcoholism in

Indexed as

dopamineGenetic Addiction Risk Severity (GARS)neurotransmittersodds ratiosopioidsReward Deficiency Syndrome (RDS)statistical validation of GARS

Identifiers

PMID36143170
PMCPMC9505592
OpenAlexW4293758661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.