Evidence map›Paper›PMID 36143134›Full record

ReviewJournal of clinical medicine2022

Correlation between Oral Lichen Planus and Viral Infections Other Than HCV: A Systematic Review.

Alberta Lucchese, Dario Di Stasio, Antonio Romano, Fausto Fiori, Guido Paolo De Felice, Carlo Lajolo, Rosario Serpico, Francesco Cecchetti, Massimo Petruzzi

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Different Approaches to Oral Lichen Planus Treatment: A Narrative Review.International journal of molecular sciences · 2026
    Review
  4. Article
  5. Article
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  9. Article
  10. Article
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  13. Review
  14. HPV related p16BMC oral health · 2024
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alberta LuccheseMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", Via Luigi de Crecchio 6, 80138 Naples, Italy.ORCID 0000-0002-2677-0869
Dario Di StasioMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", Via Luigi de Crecchio 6, 80138 Naples, Italy.ORCID 0000-0003-3401-776X
Antonio RomanoMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", Via Luigi de Crecchio 6, 80138 Naples, Italy.ORCID 0000-0002-6613-9254
Fausto FioriMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", Via Luigi de Crecchio 6, 80138 Naples, Italy.ORCID 0000-0002-1780-8896
Guido Paolo De FeliceIndependent Researcher, 81100 Caserta, Italy.ORCID 0000-0001-5597-031X
Carlo LajoloHead and Neck Department, School of Dentistry, Fondazione Policlinico Universitario A. Gemelli-IRCCS", Università Cattolica del Sacro Cuore, Largo A. Gemelli, 8, 00168 Rome, Italy.ORCID 0000-0003-4663-9734
Rosario SerpicoMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", Via Luigi de Crecchio 6, 80138 Naples, Italy.ORCID 0000-0003-2143-3799
Francesco CecchettiDepartment of Social Dentistry and Gnatological Rehabilitation, National institute Health, Migration and Poverty (NIHMP), 00153 Rome, Italy.
Massimo PetruzziInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0002-9030-3739

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis review aimed to evaluate the correlation between viral infections (HPV, EBV, HSV-1, CMV) other than HCV and oral lichen planus to assess if there is sufficient evidence to establish if these viruses can play a role in the etiopathogenesis of the disease. MATERIALS AND

methodsWe reviewed the literature using different search engines (PubMed, ISI Web of Science, and the Cochrane Library), employing MeSH terms such as "oral lichen planus" and "OLP" in conjunction with other terms. We utilized the Population, Intervention, Comparison, Outcomes, and Study design (PICOS) method to define our study eligibility criteria.

resultsA total of 43 articles of the 1219 results initially screened were included in the study. We allocated the 43 selected items into four groups, according to each related virus: HPV, EBV, HSV-1, and CMV.

conclusionsHeterogeneous results neither confirm nor exclude a direct correlation between the investigated viral infections and oral lichen planus etiopathogenesis and its feasible malignant transformation. Many viral agents can cause oral lesions and act as cancerizing agents. Future studies could be desirable to produce comparable statistical analyses and enhance the quantity and quality of the outcomes to promote the translation of research into clinical practice.

Indexed as

CMVEBVHPVHSV-1oral canceroral lichen planus

Identifiers

PMID36143134
PMCPMC9501453

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.