Evidence map›Paper›PMID 36143070›Full record

ArticleJournal of clinical medicine2022

Device for Negative Pressure Wound Therapy in Low-Resource Regions: Open-Source Description and Bench Test Evaluation.

Ramon Farré, Miguel A Rodríguez-Lázaro, Julian Gonzalez-Martin, Pedro Castro, Teresa Hospital, Yaroslau Compta, Gorka Solana, David Gozal, Jorge Otero

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Ramon FarréUnitat de Biofísica i Bioenginyeria, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, 08036 Barcelona, Spain.ORCID 0000-0002-9084-7824
Miguel A Rodríguez-LázaroUnitat de Biofísica i Bioenginyeria, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, 08036 Barcelona, Spain.
Julian Gonzalez-MartinMicrobiology Department-CDB, Hospital Clinic-ISGlobal-University of Barcelona, 08036 Barcelona, Spain.
Pedro CastroInstitut Investigacions Biomèdiques August Pi Sunyer, 08036 Barcelona, Spain.ORCID 0000-0002-6118-8970
Teresa HospitalIntensive Care Unit, Internal Medicine Department, Hospital Clínic, 08036 Barcelona, Spain.
Yaroslau ComptaInstitut Investigacions Biomèdiques August Pi Sunyer, 08036 Barcelona, Spain.
Gorka SolanaFaculdade de Engenharias e Tecnologias, Universidade Save, Maxixe, Mozambique.ORCID 0000-0002-1212-0574
David GozalDepartment of Child Health, The University of Missouri School of Medicine, Columbia, MO 65212, USA.ORCID 0000-0001-8195-6036
Jorge OteroUnitat de Biofísica i Bioenginyeria, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, 08036 Barcelona, Spain.
Hospital Clínic de Barcelona · ESUniversity of Missouri Health System · USCentro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESInstituto de Salud Carlos III · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNegative (vacuum) pressure therapy promotes wound healing. However, commercially available devices are unaffordable to most potential users in low- and middle-income countries (LMICs), limiting access to many patients who could benefit from this treatment. This study aimed to design and test a cheap and easy-to-build negative pressure device and provide its detailed open-source description, thereby enabling free replication.

methodsthe negative pressure device was built using off-the-shelf materials available via e-commerce and was based on a small pump, a pressure transducer, and the simplest Arduino controller with a digital display (total retail cost ≤ 75 US$). The device allows the user to set any therapeutic range of intermittent negative pressure and has two independent safety mechanisms. The performance of the low-cost device was carefully tested on the bench using a phantom wound, producing a realistic exudate flow rate.

resultsthe device generates the pressure patterns set by the user (25-175 mmHg of vacuum pressure, 0-60 min periods) and can drain exudate flows within the clinical range (up to 1 L/h).

conclusionsa novel, low-cost, easy-to-build negative pressure device for wound healing displays excellent technical performance. The open-source hardware description provided here, which allows for free replication and use in LMICs, will facilitate the application and wider utilization of this therapy to patients.

Indexed as

low-and middle-income countrieslow-cost medical deviceopen-source hardwarevacuum pressure therapywound healing

Identifiers

PMID36143070
PMCPMC9503864
OpenAlexW4296280725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.