Evidence map›Paper›PMID 36143066›Full record

ArticleJournal of clinical medicine2022

Evaluation of a New Echocardiographic Tool for Cardiac Output Monitoring: An Experimental Study on A Controlled Hemorrhagic Shock Model in Anesthetized Piglets.

Thibaut Markarian, Laura Grau-Mercier, Céline Occelli, Florian Ajavon, Pierre-Géraud Claret, Fabien Coisy, Xavier Bobbia

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Thibaut MarkarianEmergency Department, Timone University Hospital, Aix-Marseille University, 13005 Marseille, France.ORCID 0000-0002-5960-7240
Laura Grau-MercierEmergency Department, Nîmes University Hospital, Montpellier University, UR UM 103 IMAGINE, 30029 Nîmes, France.ORCID 0000-0003-0493-2705
Céline OccelliEmergency Department, Pasteur 2 University Hospital, Nice Côte-d'Azur University, 06000 Nice, France.
Florian AjavonEmergency Department, Nîmes University Hospital, Montpellier University, UR UM 103 IMAGINE, 30029 Nîmes, France.ORCID 0000-0002-4355-8333
Pierre-Géraud ClaretEmergency Department, Nîmes University Hospital, Montpellier University, UR UM 103 IMAGINE, 30029 Nîmes, France.
Fabien CoisyEmergency Department, Nîmes University Hospital, Montpellier University, UR UM 103 IMAGINE, 30029 Nîmes, France.ORCID 0000-0002-2812-3534
Xavier BobbiaEmergency Department, Montpellier University Hospital, Montpellier University, UR UM 103 IMAGINE, 34295 Montpellier, France.
Université de Montpellier · FRAix-Marseille Université · FRHôpital Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac output (CO) monitoring is recommended in patients with shock. The search for a reliable, rapid, and noninvasive tool is necessary for clinical practice. A new echocardiographic CO flow index (COF) is the automatic calculation of the sub-aortic VTI multiplied by the automatic calculation of the heart rate (HR). The primary objective of this study was to show the correlation between COF and CO measured by thermodilution (COth) in a controlled hemorrhagic shock model in anesthetized piglets. Secondary objectives were to show the correlation between COth and CO calculated from left outflow tract (LVOT) measurement and manual VTI (COman), and CO measured by LVOT measurement and VTIauto (COauto).

methodsProspective interventional experimental study. In seventeen ventilated and anesthetized piglets, a state of hemorrhagic shock was induced, maintained, then resuscitated and stabilized. The gold standard for CO and stroke volume measurement was thermodilution (COth).

results191 measurements were performed. The correlation coefficients (r) between COth and COF, COman, and COauto were 0.73 [0.62; 0.81], 0.66 [0.56; 0.74], and 0.73 [0.63; 0.81], respectively.

conclusionsIn this study, the COF appears to have a strong correlation to the COth. This automatic index, which takes into account the HR and does not require the measurement of LVOT, could be a rapidly obtained index in clinical practice.

Indexed as

cardiac outputechocardiographyexperimentalhemorrhagicshockultrasound

Identifiers

PMID36143066
PMCPMC9503332
OpenAlexW4296049013

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.