Evidence map›Paper›PMID 36143035›Full record

ArticleJournal of clinical medicine2022

Optimization of Tokuhashi Scoring System to Improve Survival Prediction in Patients with Spinal Metastases.

Hung-Kuan Yen, Chih-Wei Chen, Wei-Hsin Lin, Zhong-Yu Wang, Chuan-Ching Huang, Hsuan-Yu Chen, Shu-Hua Yang, Ming-Hsiao Hu

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Assessment of survival prediction after surgery in spinal metastases patients using the Global Spine Study Tumor Group (GSTSG) risk calculator; an external validation from a tertiary cancer hospital.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hung-Kuan YenDepartment of Orthopaedic Surgery, National Taiwan University Hospital, Taipei 100, Taiwan.
Chih-Wei ChenDepartment of Orthopaedic Surgery, National Taiwan University Hospital, Taipei 100, Taiwan.
Wei-Hsin LinDepartment of Orthopaedic Surgery, National Taiwan University Hospital, Taipei 100, Taiwan.
Zhong-Yu WangSchool of Medicine, National Taiwan University College of Medicine, Taipei 100, Taiwan.ORCID 0000-0002-2626-8430
Chuan-Ching HuangDepartment of Orthopaedic Surgery, National Taiwan University Hospital, Taipei 100, Taiwan.
Hsuan-Yu ChenDepartment of Orthopaedic Surgery, National Taiwan University Hospital, Taipei 100, Taiwan.ORCID 0000-0003-4998-7566
Shu-Hua YangDepartment of Orthopaedic Surgery, National Taiwan University Hospital, Taipei 100, Taiwan.ORCID 0000-0002-9879-0164
Ming-Hsiao HuDepartment of Orthopaedic Surgery, National Taiwan University Hospital, Taipei 100, Taiwan.ORCID 0000-0001-8920-2052

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPredicting survival time for patients with spinal metastases is important in treatment choice. Generally speaking, six months is a landmark cutoff point. Revised Tokuhashi score (RTS), the most widely used scoring system, lost its accuracy in predicting 6-month survival, gradually. Therefore, a more precise scoring system is urgently needed.

objectiveThe aim of this study is to create a new scoring system with a higher accuracy in predicting 6-month survival based on the previously used RTS.

methodsData of 171 patients were examined to determine factors that affect prognosis (reference group), and the remaining (validation group) were examined to validate the reliability of a new score, adjusted Tokuhashi score (ATS). We compared their discriminatory abilities of the prediction models using area under receiver operating characteristic curve (AUC).

resultsTarget therapy and the Z score of BMI (Z-BMI), which adjusted to the patients' sex and age, were additional independent prognostic factors. Patients with target therapy use are awarded 4 points. The Z score of BMI could be added directly to yield ATS. The AUCs were 0.760 for ATS and 0.636 for RTS in the validation group.

conclusionAppropriate target therapy use can prolong patients' survival. Z-BMI which might reflect nutritional status is another important influencing factor. With the optimization, surgeons could choose a more individualized treatment for patients.

Indexed as

body mass indexneoplasm stagingspine metastasessurgical oncologysurvivaltarget therapy

Identifiers

PMID36143035
PMCPMC9503025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.