Evidence map›Paper›PMID 36142973›Full record

ReviewJournal of clinical medicine2022

New Perspectives on Myeloid-Derived Suppressor Cells and Their Emerging Role in Haematology.

Nikoleta Bizymi, Andreas M Matthaiou, Angelos Matheakakis, Ioanna Voulgari, Nikoletta Aresti, Konstantina Zavitsanou, Anastasios Karasachinidis, Irene Mavroudi, Charalampos Pontikoglou, Helen A Papadaki

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nikoleta BizymiDepartment of Haematology, University Hospital of Heraklion, 71500 Heraklion, Crete, Greece.ORCID 0000-0001-5199-1519
Andreas M MatthaiouLaboratory of Molecular and Cellular Pneumonology, School of Medicine, University of Crete, 71003 Heraklion, Crete, Greece.
Angelos MatheakakisDepartment of Haematology, University Hospital of Heraklion, 71500 Heraklion, Crete, Greece.
Ioanna VoulgariDepartment of Haematology, University Hospital of Heraklion, 71500 Heraklion, Crete, Greece.ORCID 0000-0002-5338-2079
Nikoletta ArestiDepartment of Haematology, University Hospital of Heraklion, 71500 Heraklion, Crete, Greece.
Konstantina ZavitsanouDepartment of Haematology, University Hospital of Heraklion, 71500 Heraklion, Crete, Greece.
Anastasios KarasachinidisDepartment of Haematology, University Hospital of Heraklion, 71500 Heraklion, Crete, Greece.
Irene MavroudiDepartment of Haematology, University Hospital of Heraklion, 71500 Heraklion, Crete, Greece.
Charalampos PontikoglouDepartment of Haematology, University Hospital of Heraklion, 71500 Heraklion, Crete, Greece.
Helen A PapadakiDepartment of Haematology, University Hospital of Heraklion, 71500 Heraklion, Crete, Greece.ORCID 0000-0002-5146-9699

Funding

Janssen (Belgium) IBR-NC-2018-GR-0002
6 · The paper itself

Abstract

Myeloid-derived suppressor cells (MDSCs) are immature cells of myeloid origin that have gained researchers' attention, as they constitute promising biomarkers and targets for novel therapeutic strategies (i.e., blockage of development, differentiation, depletion, and deactivation) in several conditions, including neoplastic, autoimmune, infective, and inflammatory diseases, as well as pregnancy, obesity, and graft rejection. They are characterised in humans by the typical immunophenotype of CD11b

Indexed as

autoimmunitybiomarkercancerhaematologyimmune dysregulationimmunologyimmunotherapyinfectioninflammationmyeloid-derived suppressor cell (MDSC)

Identifiers

PMID36142973
PMCPMC9504532

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.