Evidence map›Paper›PMID 36142944›Full record

ArticleJournal of clinical medicine2022

Does Influenza Vaccination Reduce the Risk of Contracting COVID-19?

Francesc Alòs, Yoseba Cánovas Zaldúa, María Victoria Feijóo Rodríguez, Jose Luis Del Val Garcia, Andrea Sánchez-Callejas, Mª Àngels Colomer

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Francesc AlòsPrimary Healthcare Center, CAP Passeig de Sant Joan, Gerència Territorial de Barcelona, Institut Català de la Salut, 08010 Barcelona, Spain.ORCID 0000-0002-8350-062X
Yoseba Cánovas ZaldúaPrimary Healthcare Center, CAP Passeig de Sant Joan, Gerència Territorial de Barcelona, Institut Català de la Salut, 08010 Barcelona, Spain.
María Victoria Feijóo RodríguezBASIQ Unitat d'Avaluació, Sistemes d'Informació i Qualitat, Àmbit Barcelona Ciutat, Institut Català de la Salut, 08029 Barcelona, Spain.ORCID 0000-0001-7986-6226
Jose Luis Del Val GarciaUnitat de Suport a la Recerca Barcelona, Foundation Primary Care Research Institute Jordi Gol i Gurina (IDIAPJGol), 08025 Barcelona, Spain.ORCID 0000-0002-0391-9368
Andrea Sánchez-CallejasBASIQ Unitat d'Avaluació, Sistemes d'Informació i Qualitat, Àmbit Barcelona Ciutat, Institut Català de la Salut, 08029 Barcelona, Spain.
Mª Àngels ColomerDepartment of Mathematics ETSEA, University of Lleida, 25198 Lleida, Spain.
Institut Català de la Salut · ESInstitut Universitari d'Investigació en Atenció Primària Jordi Gol · ESUniversitat de Lleida · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The concurrent timing of the COVID-19 pandemic and the seasonal occurrence of influenza, makes it especially important to analyze the possible effect of the influenza vaccine on the risk of contracting COVID-19, or in reducing the complications caused by both diseases, especially in vulnerable populations. There is very little scientific information on the possible protective role of the influenza vaccine against the risk of contracting COVID-19, particularly in groups at high-risk of influenza complications. Reducing the risk of contracting COVID-19 in high-risk patients (those with a higher risk of infection, complications, and death) is essential to improve public well-being and to reduce hospital pressure and the collapse of primary health centers. Apart from overlapping in time, COVID-19 and flu share common aspects of transmission, so that measures to protect against flu might be effective in reducing the risk of contracting COVID-19. In this study, we conclude that the risk of contracting COVID-19 is reduced if patients are vaccinated against flu, but the reduction is small (0.22%) and therefore not clinically important. When this reduction is analysed based on the risk factor suffered by the patient, statistically significant differences have been obtained for patients with cardiovascular problems, diabetics, chronic lung and chronic kidney disease; in all four cases the reduction in the risk of contagion does not reach 1%. It is worth highlighting the behaviour that is completely different from the rest of the data for institutionalized patients. The data for these patients does not suggest a reduction in the risk of contagion for patients vaccinated against the flu, but rather the opposite, a significant increase of 6%. Socioeconomic conditions, as measured by the MEDEA deprivation index, explain increases in the risk of contracting COVID-19, and awareness campaigns should be increased to boost vaccination programs.

Indexed as

comorbidityCOVID-19health status disparitiesinfluenza vaccinespublic healthsocial determinants of health

Identifiers

PMID36142944
PMCPMC9504696
OpenAlexW4295213421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.