Evidence map›Paper›PMID 36142889›Full record

ArticleInternational journal of molecular sciences2022

Ultrasonic-Assisted Synthesis of Benzofuran Appended Oxadiazole Molecules as Tyrosinase Inhibitors: Mechanistic Approach through Enzyme Inhibition, Molecular Docking, Chemoinformatics, ADMET and Drug-Likeness Studies.

Ali Irfan, Ameer Fawad Zahoor, Shagufta Kamal, Mubashir Hassan, Andrzej Kloczkowski

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  4. Total Syntheses of Deuterated Drugs: A Comprehensive Review.Topics in current chemistry (Cham) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ali IrfanDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0002-8977-3303
Ameer Fawad ZahoorDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0003-2127-8848
Shagufta KamalDepartment of Biochemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.
Mubashir HassanThe Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH 43205, USA.
Andrzej KloczkowskiThe Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH 43205, USA.ORCID 0000-0003-1002-5095

Funding

Novel Use of Genome Information to Understand MutationsR01HG012117 · NHGRI · IOWA STATE UNIVERSITY · PI JERNIGAN, ROBERT L, KLOCZKOWSKI, ANDRZEJ · 2021 to 2025
$2.3M
Protein Sequence MatchingR01GM127701 · NIGMS · IOWA STATE UNIVERSITY · PI JERNIGAN, ROBERT L, KLOCZKOWSKI, ANDRZEJ · 2018 to 2021
$1.4M
National Institute of Health DBI1661391; R01GM127701; R01HG012117NHGRI NIH HHS R01 HG012117NIGMS NIH HHS R01 GM127701
6 · The paper itself

Abstract

Furan-oxadiazole structural hybrids belong to the most promising and biologically active classes of oxygen and nitrogen containing five member heterocycles which have expanded therapeutic scope and potential in the fields of pharmacology, medicinal chemistry and pharmaceutics. A novel series

Indexed as

Antineoplastic AgentsBenzofuransAmidesAscorbic AcidCheminformaticsDose-Response Relationship, DrugEnzyme InhibitorsFuransMolecular Docking SimulationMolecular StructureMonophenol MonooxygenaseNitrogenOxadiazolesOxygenStructure-Activity RelationshipUltrasonicsAmidesAntineoplastic AgentsAscorbic AcidBenzofuransEnzyme InhibitorsFuransMonophenol MonooxygenaseNitrogenOxadiazolesOxygenADMET studychemoinformaticsfuran-oxadiazole moleculesmolecular dockingstructure-activity relationshiptyrosinase inhibitorsultrasonic-assisted green synthesis

Identifiers

PMID36142889
PMCPMC9500974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.